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UBPBio are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue u
UBPBio公司新闻
Ub-Rhodamine 110 is a quenched, fluorescent substrate for deubiquitinating enzymes. Cleavage of the amide bond between the C-terminal glycine of ubiquitin and rhodamine110 results in an increase in rhodamine fluorescence at 535 nm (Exc. 485 nm). Addi...
2019-02-12
阅读量(6)
Rapamycin is an antifungal and immunosuppressant. Rapamycin was originally used an antifungal antibiotic. It is now known as a specific inhibitor of mTOR. Rapamycin binds to FK-binding protein 12 (FKBP12) and forms the rapamycin-FKBP12 complex, which...
2019-02-17
阅读量(0)
Anti-β-Tubulin (BT7R) Loading Control Mouse Monoclonal Antibody Additional Information Product Name: Anti-beta-Tubulin Also Known As: Anti-β-Tubulin (BT7R) Loading Control Mouse Monoclonal Antibody Catalog No.: Y1061 Size: 100 µg Molecul...
2019-02-26
阅读量(3)
Ube2M is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for conjugation of the Ub-like protein NEDD8 to protein substrates. This E2 is unique from Ube2F in the fact that it does not need to complex with an E3 in order to conjug...
2019-03-07
阅读量(1)
IPTG, Isopropyl β-D-1-thiogalactopyranoside, binds the lac repressor and induces expression of β-galactosidase in E. coli. IPTG is widely used to induce the expression of cloned genes under the control of the lac operon and to screen blue/white colon...
2019-03-15
阅读量(25)
MK-2206 dihydrochloride is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM, respectively. Inhibits auto-phosphorylation of both Akt T308 and S473. MK-2206 also prevents Akt-mediated phosphorylation of downstream signaling molec...
2019-03-17
阅读量(5)
Ube2G2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It has been shown to complex with the E3 ligase called GP78 to catalyze K48 – linked Ub chains. This is an endoplasmic reticulum...
2019-03-21
阅读量(3)
Agarose 6B is a bead-formed agarose-based gel filtration matrix. It is also used for coupling affinity ligands to the matrix Additional Information Product Name: Agarose 6B Catalog No.: P4010-100 Size: 100 ml Bead (Geometry, size): 50 - 16...
2019-04-01
阅读量(3)
This kit is designated for monitoring CHIP-mediated ubiquitination of user-supplied misfolded proteins. CHIP is an E3 ubiquitin ligase that directly or via Hsp70 interacts with misfolded proteins and promotes their polyubiquitination, which targets m...
2019-04-10
阅读量(12)
This products is a fluorescence polarization (FP) assay reagent, which is based on a 5-carboxytetramethylrhodamine (TAMRA) modified Lys-Gly sequence that is linked to ubiquitine via a native isopeptide bond with the lysine side-chain. Typical substra...
2019-04-21
阅读量(0)
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