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UBPBio are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue u
UBPBio公司新闻
N-terminal TARMA-Ub (also called TARMA-Ub) is a fluorescent Ub, in which TAMRA (5-tetramethylrhodamine) is covalently conjugated on the N-terminus of Ub. All seven lysine residues in TARMA-Ub are available for ubiquitination. This product can be used...
2020-07-07 阅读量(4)
Ubiquitin C-terminal hydrolase L3 (UchL3) is a deubiquitinase enzyme (DUB), which performs hydrolysis of the bond at the C terminus of the ubiquitin and trims down the polyubiquitin chain into monomers. UchL3 has been found to also process a ubiquiti...
2020-07-20 阅读量(0)
CM XPure Agarose Resin is part of Ion exchange Resin which is widely used in biomedical and bioengineering for separation and purification of proteins, nucleic acids and polypeptides. The base matrix of CM XPure Agarose Resin is 6% highly cross-linke...
2020-08-01 阅读量(4)
CAL-101 (idelalisib or GS-1101) is a potent inhibitor of the delta isoform of the 110 kDa catalytic subunit of class I phosphoinositide-3 kinase (PI3K) with IC50 of 2.5 nM in cell-free assays. CAL-101 decreases pAktS473, pAktT308, and the downstream ...
2020-09-05 阅读量(10)
PMSF (phenylmethylsulfonyl Fluoride) is a serine protease inhibitor that reacts with the catalytic serine residue of trypsin, chymotrypsin, thrombin and papain at the concentration of 0.1-1 mM. PMSF has a relatively short life time in aqueous solutio...
2020-09-14 阅读量(6)
ONC201 (also called TIC10) is a potent TRAIL inducer by inhibition of ERK and AKT. ONC201 promotes nuclear localization of Foxo3a, which then enhances TRAIL transcription to induce cancer cell death. ONC201 is orally active. Additional Information ...
2020-09-23 阅读量(3)
PS-341 is a specific, reversible and cell permeable dipeptide boronic acid inhibitor of the chymotrypsin-like activity of the proteasome (Ki=0.6nM). It inhibits proliferation of various tumor cell lines with nanomolar potency. Its commercial version ...
2020-10-04 阅读量(1)
IPTG, Isopropyl β-D-1-thiogalactopyranoside, binds the lac repressor and induces expression of β-galactosidase in E. coli. IPTG is widely used to induce the expression of cloned genes under the control of the lac operon and to screen blue/white colon...
2020-10-15 阅读量(14)
6xHis-non-cleavable K63 polyUb chains are made of the 6xHis-Ub(L73P) mutant, this substitution makes the formed polyubiquitin chains to be resistant to the majority of deubiquitinating enzymes. Additional Information Product Name: 6xHis-Non-clea...
2020-10-27 阅读量(6)
RING-finger 4 (RNF4), also known as Snurf, is an E3 ubiquitin ligase. RNF4 is composed of four SUMO interaction motifs (SIMs) at the N-terminal and a RING domain at the C-terminal. The SIM domains prefer binding polySUMO chains; RNF4 functions to ubi...
2020-11-08 阅读量(9)
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