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UBPBio are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue u
UBPBio公司新闻
Ub chains are formed by conjugating the C-terminal glycine residue of Ub onto any of seven internal lysine residues or the amino group of the previous Ub. Ub chains are classified by the lysine residue used to link Ubs; different Ub chain topologies ...
2019-01-03 阅读量(2)
Tobacco Etch Virus (TEV) protease is a cysteine protease that is commonly used to remove fusion tags, including His, GST and MBP, at the N or C termini of recombinant proteins. TEV protease specifically recognizes a seven amino acid sequence Glu-Asn-...
2019-01-05 阅读量(2)
Z-VAD-FMK is a cell-permeable pan caspase inhibitor that irreversibly binds to the catalytic site of caspases and can inhibit induction of apoptosis. Additional Information Product Name: Z-VAD-FMK Also Known As: N/A Catalog No.: F7110 Siz...
2019-01-10 阅读量(2)
PI31 is a proline-rich protein and its C-terminal region can act as a potent 20S proteasome inhibitor in vitro. In cells, it plays a role in regulating 26S proteasome assembly and activity. Additional Information Product Name: 6xHis-PI31 Also...
2019-01-12 阅读量(0)
The E2 Screening Kit is developed for identification of the E2 Ub-conjugating enzyme(s) for a specific E3 Ub ligase and/or a protein substrate. N/A Additional Information Product Name: Customized E2 Screening Kit Also Known As: N/A Catalog N...
2019-01-15 阅读量(4)
Ixazomib (MLN2238) (commercial name: Ninlaro®) is the first and only FDA-approved oral proteasome inhibitor for the treatment of multiple myeloma. It reversibly inhibits the chymotrypsin-like activity of proteasomes with IC50 of 3.4 nM in cell-free a...
2019-01-18 阅读量(7)
TNFalpha (Tumor necrosis factor alpha) is produced by immune and epithelial cells. It plays important roles in regulating inflammation, apoptosis, and immune response. It exerts its function mainly by binding of two cell surface receptors TNFR1 and T...
2019-01-20 阅读量(12)
Ube2V2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Ube2V2 is the human homolog of yeast Mms2 and shares 50% amino acid sequence identity. Its main function is to be used in DNA re...
2019-01-23 阅读量(4)
Neural precursor cell expressed developmentally downregulated 8 (Nedd8) is a ubiquitin-like protein. Nedd8 can be conjugated on culin proteins and this modification plays a key role in activation of culin-based E3 ubiquitin ligases. SENP8 (also calle...
2019-01-27 阅读量(8)
Used as a solidifying agent, mainly used for preparing microbiological LB plate at 1.5%.Specification:Gel Strength (1.5%) ≥ 800 g/cm²Melt Point 85 ℃Gelation Point 32-39 ℃ Additional Information Product Name: Agar Also Known As: No Catalog No...
2019-02-05 阅读量(3)
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