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外泌体参与细胞间通讯,目前对外泌体的研究兴趣日益增长,小编整理一些外泌体相关的数据库,供研究者学习使用。
ExosomeDatabase
www.ExosomeData.com
EVpedia--Databaseofexosomalproteome,transcriptome,andlipidome
http://www.evpedia.info/
Apublicdatabaseforextracellularvesiclesresearch.
EVpediaisanintegratedandcomprehensiveproteome,transcriptome,andlipidomedatabaseofEVsderivedfromarchaea,bacteria,andeukarya,includinghuman.
EVpediaprovidesanarrayoftools,suchassearchandbrowsetoolsforvesicularproteins,comparisonofvesiculardatasetsbyorthologidentification,GeneOntologyenrichmentanalysesandnetworkanalysesofvesicularproteins.FurThermore,EVpediaprovidesdatabasesofvesicularmRNAs,miRNAs,andlipids.Thus,EVpediamightserveasausefulcommunityresourcetotriggertheadvancementofsystematicandcomprehensivestudiesofEVsandtounveilthefundamentalrolesofEVs.
ExoCarta--Databaseofexosomalproteins,RNAandlipids.
www.exocarta.org/
ExoCarta:databaseofexosomalproteins,RNAandlipids.
ExoCarta,anexosomedatabase,provideswiththecontentsthatwereidentifiedinexosomesinmultipleorganisms.
Vesiclepedia--Databaseofexosomalproteins,RNAandlipids
http://www.microvesicles.org/
Acommunitycompendiumforextracellularvesicles
Vesiclepedia,amanuallycuratedcompendiumofmoleculardata(lipid,RNAandprotein)identifiedindifferentclassesofEVs.Currently,Vesiclepediacomprises35,264protein,18,718mRNA,1,772miRNAand342lipidentriesencompassedfrom341independentstudiesthatwerepublishedoverthepastseveralyears.
ExosomeGeneOntologyAnnotationInitiative
http://www.ebi.ac.uk/GOA/exosome
Thisinitiative,undertakenbytheUniProtcuratorsattheEBI,involvesthemanualassignmentofGOannotationstohumanexosomalproteinsbycuratorsreADIngthescientificliteratureandassigningtotheproteinsGOtermsthatdescribetheirBIOLOGicalroles.CuratorsworkingonthisprojectarerequestingnewGOtermsspecifictoexosomeproteinbiologytofullycaptureliteraturefindings.
exoRBase--DatabaseofexosomalcircRNA、LncRNAandmRNA
http://www.exorbase.org/
exoRBaseisarepositoryofcircularRNA(circRNA),longnon-codingRNA(lncRNA)andmessengerRNA(mRNA)derivedfromRNA-seqdataanalysesofhumanbloodexosomes.Experimentalvalidationsfrompublishedliteraturearealsoincluded.
exoRBasefeaturestheintegrationandvisualizationofRNAexpressionprofilesbasedonnormalizedRNA-seqdataspanningbothnormalindividualsandpatientswithdifferentdiseases.
UrinaryExosomeProteinDatabase
https://hpcwebapps.cit.nih.gov/ESBL/Database/Exosome/
ThisdatabaseofurinaryexosomeproteinsisbasedonpublishedproteinmassspectrometrydatafromtheNHLBIEpithelialSystemsBiologyLaboratory(ESBL).Alldataarefromurinaryexosomesisolatedfromhealthyhumanvolunteers.
Thiscurrentdatabasecontainsproteinidentificationofhumanurinaryexosomesusingtwodifferentmassspectrometeranalyzers.
exRNAAtlas--DatabaseofexosomalRNA
http://exrna-atlas.org/
TheexRNAAtlasisthedatarepositoryoftheExtracellularRNACommunicationConsortium(ERCC),whichincludessmallRNAsequencingandRT-qPCR-derivedexRNAprofilesfromhumanandmousebiofluids.AllRNA-seqdatasetsareprocessedusingversion4oftheexceRptsmallRNA-seqpipelineandERCC-developedqualitymetricsareuniformlyappliedtothesedatasets.
editedbyAlexfromUmibio(Shanghai)Co.Ltd
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