YULihua;ZHANGCheng;LIUMinya;JIANGMing;FANGJianmin;BiomedicalResearchCentre,TongjiUniversitySuzhouInstitute;Exosomesarenano-sizedvesicleswithlipidbilayer,containinglargeamountsofbioactivemolecules.Non-smallcelllungcancerderivedexosomes,interactingwithothercellsofthetumormicroenvironment,modulatetumorprogression,angiogenesis,metastasis,andimmuneescape.Exosomesinnon-smallcelllungcancer(NSCLC)canbeusedasexcellentbioMarkerswithgreatpotentialsforNSCLCdiagnosisandprognosis,sincetheycontaintumor-specificproteinsandmiRNAswhicharedifferentiallyexpressed.Furtherstudiesareneededtoprobethekeycomponentsfortumorgenesisandprogress.Someissuesincludingthestandardizationofexosomesapplicationshouldbeconsideredparticularlytopromoteitsclinicalapplication.【Fund】：苏州市科技计划项目(ZXY2012029)
【CateGoryIndex】：R734.2
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