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我国旅美科学家陈清奇博士创立的MedKoo美帝药库医药公司目前正在建立全球第一个小分子抗癌药库。 MedKoo是一家以研发、生产和销售小分子抗癌化合物为主的医药科技公司。
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为全球所有从事抗癌药物研究和开发的制药公司，高校，研究院所，政府相关机构提供与抗癌药物分子相关的产品、试剂和技术服务。
技术核
MedKoo公司新闻
WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist. WZ811 shows subnanomolar potency (EC50 = 0.3 nM) in an affinity binding assay. In addition, when subjected to in vitro functional evaluation, WZ811 efficiently inhibits CXCR4/stromal cell...
2016-11-20
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Nepicastat, also known as SYN117 and RS-25560-197, is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. It has been studied as a possible treatment for congestive heart failure, and appe...
2016-12-31
阅读量(6)
WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor with potential anticancer activity. WZ8040 is about 30-fold more potent against EGFR T790M, and up to 100-fold less potent against wild-type EGFR, than other quinazoline-based EGFR i...
2017-01-26
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ZM336372 is a Raf-1 activating agent, has been shown to cause growth inhibition and suppression of hormone secretion in a neuroendocrine cell line. ZM336372 causes growth inhibition, suppression of hormone secretion, and up-regulation of cell cycle i...
2017-02-23
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F-1670警告：本产品仅供研究使用，不得用于人类或兽医。MedKoo CAT#：575264CAS#：68398-03-8描述：F-1670 是一种潜在的治疗剂。 化学结构F-1670CAS # 68398-03-8InstructionTheoretical AnalysisMedKoo Cat#: 575264Name: F-1670CAS#: 68398-03-8Chemical Formula: C17H21NO3 Exact Mass: 287.1521Molecular Weigh...
2017-04-11
阅读量(45)
XL-418 is a selective, orally active small molecule, targeting protein kinase B (PKB or AKT) and ribosomal protein S6 Kinase (p70S6K), with potential antineoplastic activity. XL418 inhibits the activities of PKB and p70S6K, both acting downstream of ...
2017-04-27
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R1530featured警告：本产品仅供研究使用，不供人类或兽医使用。MedKoo CAT#：202391CAS#：882531-87-5描述：R1530 是一种吡唑并苯二氮卓类小分子，具有潜在的抗血管生成和抗肿瘤活性。 R1530 也是一种有丝分裂血管生成抑制剂 (MAI)，可抑制参与血管生成的多种受体酪氨酸激酶，例如血管内皮生长因子受体 (VEGFR)-1、-2、-3、血小板衍生生长因子受体 (PDGFR) β ‚ FMS 样酪氨酸激酶 (Flt)-3 和成纤维细胞生长因子受体 (FGFR...
2017-04-27
阅读量(51)
所有产品特色产品最新产品研究领域16血管生成Bcr-AblBTKEGFRFAKFGFFLT3HIFJAKPDGFRSrcSykVDAVEGFRBcl-2test3demo3338细胞凋亡Caspasec-RETIAPMdm2p53PERKSurvivinTNF-alpha2自噬LRRK2APC9细胞周期极光激酶CDKChkc-MycPLK RhoROCKWee1Akt11细胞骨架信号转导Bcr-Abl动力蛋白FAKHSP整合素驱动蛋白微管PAKPKCWnt/β-连环蛋白ATM/ATR8DNA损伤...
2017-05-11
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Ceanothic acid, the A-1 homologue of betulinic acid, is isolated from Ceanothus americanus. Synthesized compounds from ceanothic acid have been shown to inhibit Epstein-Barr virus early antigen activation in anti-cancer research. It also demonstrates...
2017-05-13
阅读量(8)
ZM336372 is a Raf-1 activating agent, has been shown to cause growth inhibition and suppression of hormone secretion in a neuroendocrine cell line. ZM336372 causes growth inhibition, suppression of hormone secretion, and up-regulation of cell cycle i...
2017-05-22
阅读量(0)
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