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BioX cell/InVivoMAb antimouse/human VLA4 (CD49d)/BE0071/100MG
ThePS/2monoclonalantibodyreactswithhumanandmouseVLA-4αchainalsoknownasCD49dandintegrinalpha4.VLA-4isa150kDaglycoproteinbelongingtotheintegrinfamilythatisexpressedbymanycelltypesincludingTandBlymphocytes,monocytes,eosinophils,basophils,mastcells,thymocytes,NKcells,anddendriticcells.Integrinα4associateswithintegrinβ7toformintegrinα4β7alsoknownasLPAM-1aswellasintegrinβ1(CD29)toformintegrinα4β1alsoknownasVLA-4.Integrinα4playsrolesinadhesionandTcellco-stimulation.Integrinα4ligandsincludeVCAM-1,MAdCAM-1,andfibronectin.ThePS/2antibodyisusefulforinvivoandinvitroVLA-4neutralization.
| Isotype | RatIgG2b, κ |
| RecomendedIsotypeControl(s) | InVivoMAbratIgG2bisotypecontrol,anti-keyholelimpethemocyanin |
| RecommendedInVivoPureDilutionBuffer | InVivoPurepH6.5DilutionBuffer |
| Immunogen | MouseP815mastcells |
| ReportedApplications |
|
| Endotoxin |
|
| Purity |
|
| Formulation |
|
| Sterility | 0.2μMfiltered |
| Production | Purifiedfromtissueculturesupernatantinananimalfreefacility |
| Purification | ProteinG |
| Storage | Undilutedat4°Cinthedark |
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