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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Product Name | 14-3-3 Monoclonal Antibody |
---|---|
Background | 14-3-3 proteins interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms (gamma,epsilon,beta,zeta,sigma,theta,tau) that form multiple homo- and hetero- dimmers. 14-3-3 proteins display the highest expression levels in the brain,and have been implicated in several neurodegenerative diseases,including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody recognizes 14-3-3 tau (YWHAQ),eta (YWHAH),and zeta (YWHAZ),but not epsilon (YWHAE). |
Host | Mouse |
Clone | 954 |
Isotype | IgG1 |
Immunogen | Fusion protein of 14-3-3 |
Synonyms | 14 3 3,14 3 3 protein T cell,14 3 3 protein tau,14 3 3 protein theta,14-3-3 tau,HS1,Protein HS1,YWHAQ |
Reactivity | Human, Rat |
Applications | ELISA, IF, IHC, WB |
Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
SwissProt | P27348 |