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(+)-EtomoxirSodiumSaltHydrate(Catalog#:A-1672)(Target:CPT1)(CAS#:828934-41-4)...(+)-JQ-1(Catalog#:A-1291)(Target:)(CAS#: 1268524-70-4 )(+)-JQ1isaBETpotentBETbromodomainInhibitor.Bromodomainandextraterminaldomain(BET)prote...3-DeazaneplanocinA(Catalog#:A-1417)(Target:EZH2)(CAS#:120964-45-6 )4SC-202(Catalog#:A-1971)(Target:)(CAS#:910462-43-0 )4SC-202isanorallybioavailablebenzamideandinhibitorofhumanclassIhistonedeacetylases(HDA...5'-Deoxy-5-fluorouridine(Catalog#:A-1915)(Target:)(CAS#:3094-09-5 )Doxifluridine,alsoknownas5'-Deoxy-5-fluorouridine,isafluoropyrimidinederivativeandoralpro...A-1155463(Catalog#:A-6045)(Target:BCL-XL)(CAS#:1235034-55-5)A-1155463ispotentandselectiveBCL-xLinhibitor......A-1210477(Catalog#:A-9036)(Target:MCL-1)(CAS#:1668553-26-1)A-1210477isapotentandselectiveMCL-1inhibitor.A-1210477showstodisrupttheinteractionbetw...A-1331852(Catalog#:A-6046)(Target:BCL-XL)(CAS#:1430844-80-6)A-1331852isapotentandselectiveBCL-XL-selectiveinhibitor....A-395(Catalog#:A-1056)(Target:EED)(CAS#:)A-395isapotentantagoNISToftheH3K27me3bindingfunctionsofEED(EmbryonicEctodermDevelopmen...ABBV-075(Mivebresib)(Catalog#:A-6007)(Target:BET)(CAS#:1445993-26-9)ABBV-075(Mivebresib)isapotentBETinhibitor(bromodomain(BRD)-containingproteind)withpotenti...ABBV-621(Catalog#:A-1066)(Target:TRAIL)(CAS#:)ABBV-621isanintravenously-administeredTRAILreceptoragonist....ABBV-744(Catalog#:A-1666)(Target:BET)(CAS#:)ABBV-744isafirst-in-classhighlyBDII-selectiveBETbromodomaininhibitor....ABC-1183(Catalog#:A-6049)(Target:CDK9,GSK3)(CAS#:1042735-18-1)ABC-1183isaninhibitforCDK9andGSK3....ABC294640(Catalog#:A-1269)(Target:)(CAS#:915385-81-8 )ABC294640,alsoknownasOpaganib,isanorallyavailable,aryladamantanecompoundandselectiveinh...ABL-001(Asciminib)(Catalog#:A-1967)(Target:BCR-ABL)(CAS#:1492952-76-7)ABL-001(Asciminib)isapotentallostericinhibitorofBCR-ABL.ABL001preventsemergenceofresist...ABT-199(Venectoclax)(Catalog#:A-1231)(Target:BCL-2)(CAS#:1257044-40-8)ABT-199(Venetoclax)isanorallybioavailable,andselectivesmallmoleculeinhibitoroftheanti-a...ABT-263(Navitoclax)(Catalog#:A-1001)(Target:BCL-2)(CAS#:923564-51-6)ABT-263(Navitoclax)isanorallybioavailable,small-moleculeantagonistofasubsetofBCl-2(B-ce...ABT-492(Catalog#:A-1620)(Target:)(CAS#:189279-58-1 )Delafloxacin,alsoknownasABT-492,RX-3341andWQ-3034,isanon-zwitterionicfluoroquinoloneant...ABT-494(Upadacitinib)(Catalog#:A-6104)(Target:JAK1)(CAS#:1310726-60-3)ABT-494(Upadacitinib)isapotentandselectiveJAK1inhibitorindevelopmentforrheumatoidarthri...ABT-578(Catalog#:A-1618)(Target:)(CAS#: 221877-54-9 )Zotarolimus,alsoknownasABT-578andA-179578,isanimmunosuppressant.Itisasemi-syntheticde...ABT-737(Catalog#:A-1002)(Target:PARP)(CAS#:852808-04-9)ABT-737isaBH3mimeticinhibitorofBcl-xL,Bcl-2andBcl-wwithEC50of78.7nM,30.3nMand197....ABT-767(Catalog#:A-1244)(Target:PARP)(CAS#:)ABT-767isanorallyavailableinhibitorofthenuclearenzymespoly(ADP-ribose)polymerase(PARP)1...ABT-809(Catalog#:A-1389)(Target:EGFR)(CAS#:)ABT-809isanEGFRtyrosinekinaseinhibitor....ABT-888(Catalog#:A-1910)(Target:PARP)(CAS#:912444-00-9(freebase))ABT-888isapoly(ADP-ribose)polymerase(PARP)-1and-2inhibitorwithchemosensitizingandantitu...AC-220(Quizartinib)(Catalog#:A-1518)(Target:FLT3)(CAS#:950769-58-1(freebase))AC220(Quizartinib)isanorallyavailableFLT3/STK1inhibitorwithpotentialantineoplasticactiv...AC-710(Catalog#:A-1972)(Target:)(CAS#:1351522-04-7 )AC710isapotent,orallyactive,andselectiveplatelet-derivedgrowthfactorreceptor-familykinas...ACP-196(Catalog#:A-1968)(Target:BTK)(CAS#:1420477-60-6)ACP-196(Acalabrutinib)isanorallyavailableinhibitorofBruton’styrosinekinase(BTK)withp...AEE-788(Catalog#:A-1105)(Target:EGFR)(CAS#:497839-62-0)AEE-788isanorallybioavailablemultiple-receptortyrosinekinaseinhibitor.AEE788inhibitsphosp...AEW-541(NVP-AEW-541)(Catalog#:A-1911)(Target:IGFR)(CAS#:475489-16-8)AEW-541(NVP-AEW-541)isanovel,potentIGF-IRkinaseinhibitor.AEW541abrogatesIGF-I-mediateds...AG-120(Ivosidenib)(Catalog#:A-1323)(Target:IDH1)(CAS#:1448347-49-6 )AG-120(Ivosidenib)isanorallyavailableinhibitorofisocitratedehydrogenasetype1(IDH1),with...AG-221(Enasidenib)(Catalog#:A-1324)(Target:IDH2)(CAS#:1446502-11-9)AG-221(Enasidenib)isapotentandselectiveIDH2inhibitorwithpotentialanticanceractivity(IDH...AG-881(Vorasidenib)(Catalog#:A-6078)(Target:IDH1,IDH2 )(CAS#:1644545-52-7)AG-881(Vorasidenib)isapotentandselectiveorallyavailableinhibitorofmutatedformsofbothi...AGI-6780(Catalog#:A-1328)(Target:IDH)(CAS#:1432660-47-3)AGI-6780isapotentandselectiveIDH2inhibitor.AGI-6780inhibitsthetumor-associatedmutantIDH...Alimta(Catalog#:A-2002)(Target:)(CAS#:357166-29-1 )Pemtrexeddisodiumisthedisodiumsaltofasyntheticpyrimidine-basedantifolate.Pemetrexedbinds...ALLOPREGNANOLONE(Catalog#:A-9118)(Target:γ-aminobutyricacid)(CAS#:516-54-1)Allopregnanoloneisaneurosteroidmetaboliteofprogesterone.Itisanallostericmodulatorofinhi...AM-5992(Catalog#:A-1611)(Target:)(CAS#:1169694-98-7)AMG-110(Catalog#:A-1600)(Target:)(CAS#:)AMG-176(Catalog#:A-6056)(Target:MCL-1)(CAS#:1883727-34-1 )AMG-176isaninhibitorofinducedmyeloidleukemiacelldifferentiationproteinMCL-1(myeloidcel...AMG-208(Catalog#:A-1242)(Target:c-Met)(CAS#:1002304-34-8 )AMG-208isaselectivesmall-moleculeinhibitoroftheproto-oncogenec-Metwithpotentialantineopl...AMG-232(Catalog#:A-1354)(Target:MDM2)(CAS#:1352066-68-2 )AMG232isanextremelypotentMDM2inhibitor....AMG-337(Catalog#:A-1601)(Target:c-Met)(CAS#:1173699-31-4)AMG-337isanorallybioavailableinhibitoroftheproto-oncogenec-Metwithpotentialantineoplast...AMG-47a(Catalog#:A-1376)(Target:)(CAS#: 882663-88-9 )AMG-47aisapotentinhibitorofLckandTcellproliferation.AMG-47acouldpromotethedegradation...AMG-51(Catalog#:A-6047)(Target:PI3K)(CAS#:890019-63-3)AMG-51isapotentandselectivepanclassIPI3KinhibitorexhibitingIC50valuesof8,11,2,and...AMG-511(Catalog#:A-1352)(Target:PI3K)(CAS#:1253573-53-3)AMG-511isanorallybioavailable,highlypotentandselectivepan-classIphosphatidylinositol-3ki...AMG-517(Catalog#:A-1088)(Target:TRPV1)(CAS#:659730-32-2)AMG-517isapotentandselectiveTRPV1antagonist,andantagonizescapsaicin,proton,andheatacti...AMG-900(Catalog#:A-1602)(Target:)(CAS#:945595-80-2 )AMG900isasmall-moleculeinhibitorofAurorakinasesA,BandCwithpotentialantineoplasticac...AMG-925(FLX925)(Catalog#:A-1353)(Target:FLT3;CDK4)(CAS#:1401033-86-0 )AMG-925(FLX925)isapotentandorallybioavailabledualFLT3/CDK4inhibitorwithIC50of1nMand...Andrographolide(Catalog#:A-3001)(Target:)(CAS#:5508-58-7 )Andrographolideisalabdanediterpenoidthatisthemainbioactivecomponentofthemedicinalplant...Antroquinonol(Catalog#:A-1379)(Target:)(CAS#:1010081-09-0 )Antroquinonolispotentiallyforthetreatmentofnon-smallcelllungcancer....AP-23573(Ridaforolimus)(Catalog#:A-1004)(Target:mTOR)(CAS#:572924-54-0 )AP-23573(Ridaforolimus)isasmall-moleculeinhibitoroftheproteinmTOR,aproteinthatactsasa...AP-24534(Ponatinib)(Catalog#:A-1158)(Target:BCR-ABL)(CAS#:943319-70-8(freebase))AP-24534(Ponatinib)isanorallybioavailablemultitargetedreceptortyrosinekinase(RTK)inhibito...AP-26113(Brigatinib)(Catalog#:A-1157)(Target:ALK;EGFR)(CAS#:1197953-54-0)AP-26113(Brigatinib)isanorallyactive,potentandselectivedualALK/EGFRinhibitor.AP-26113bi...Apigenin(Catalog#:A-3002)(Target:)(CAS#:520-36-5 )Apigenin(4Â’,5,7-trihydroxyflavone),foundinmanyplants,isanaturalproductbelongingtothefl...AR-12(OSU-03012)(Catalog#:A-1209)(Target:)(CAS#:742112-33-0(AR-12))AR-12,alsoknownasOSU-03012,isanorallyavailable,targetedanti-canceragentthathasbeensho...ARN-509(Apalutamide)(Catalog#:A-6036)(Target:AndrogenReceptor)(CAS#:956104-40-8)ARN-509(Apalutamide)isanandrogenreceptorantagonistwithpotentialantineoplasticactivity.ARN...ARQ-087(Derazantinib)(Catalog#:A-6001)(Target:FGFR)(CAS#:1234356-69-4)ARQ-087(Derazantinib)isanorallybioavailableinhibitorofthefibroblastgrowthfactorreceptor...ARQ-092(Miransertib)(Catalog#:A-1604)(Target:AKT)(CAS#:1313881-70-7)ARQ-092(Miransertib)isanoralactivie,potentandselectiveAKTinhibitorwithIC50values:5.0n...ARQ-197(Tivantinib)(Catalog#:A-1109)(Target:c-Met)(CAS#:905854-02-6)ARQ-197(Tivantinib)isanorallybioavailablesmallmoleculeinhibitorofc-Metwithpotentialanti...ARQ-621(Catalog#:A-1605)(Target:)(CAS#:1095253-39-6 )ARQ-621isanallosteric,potentandselectiveinhibitorofEg5,amicrotubule-basedATPasemotorp...ARQ-736(Catalog#:A-1606)(Target:)(CAS#: 1228237-57-7 )ARQ736isapotentandselectiveBRAFinhibitor.ARQ736isselectivelypotentinkillingcancerc...ARRY-382(Catalog#:A-1607)(Target:)(CAS#:)ARRY-382isasmallmoleculeandorallyavailableinhibitorofcolony-stimulatingfactor-1receptor...ARRY-614(Catalog#:A-1410)(Target:)(CAS#:945614-12-0 )Pexmetinib,alsoknownasARRY-614,isanorallybioavailablesmall-moleculeinhibitorofp38andT...ARS-1620(Catalog#:A-1671)(Target:K-RAS(G12C))(CAS#:1698055-85-4)ARS-1620isapotentandirreversIBLeinhibitorofmutantK-RAS(G12C)throughacovalentbondwitht...Artemether(Catalog#:A-3022)(Target:)(CAS#:71963-77-4)