Enzyme

Target

Assay

Kinase

ABL1s,ACK,AKTs,AMPKs,Auroras,AXL,BRK,BXM,CAMKs,CDKs,CyclinA2,DAPK1,EGFRs,ERKs,FAK,FGFR,FLT,GRK,GSKs,HER,HIPK,IKKs,JNKs,LYNB,MAPKAPK2/3/5,p38s,ROCKs,SLK,TNIK,ULK1,VRK2,ZAK,etal.

ADP-Glo

Methyl-lysine

CBX1,L3MBTL1

AlphaScreen/Fluorogenic

Heatshockprotein

HSP90α,HSP90ß

AlphaScreen

Deacetylases

HDAC1/2/3/4/5/6/7/8/9,SIRT1/2/3/5

Fluorogenic

PARPs

PARP1/2/3/6/7/10/11/14/15,TNKS1/S2

Chemiluminescence/Colorimetric

Protease

DPP3/4/7/8/9,FAP,POP,Renin,Caspase3/6/7/8

Fluorogenic

Phosphodiesterase

PDEs,Autotaxin

TR-FRET/FP/Fluorogenic

Demethylases

FBXL10/11,JARID1A/B/C/D,JMJD1A,JMJD2s,JMJD3,LSD1,PHF8,TET1,TET2,UTX

AlphaScreen/Chemiluminescent

Methyltransferases

DNMTs,DOT1L,EHMT1/GLP,EZHs,G9a,Histones,MLL1,NSDs,PRMTs,SetDB1,SUV39H,SMYDs,SETs,etal.

Chemiluminescence

Bromodomains

ATADs,BAZ2B,BPTF/FALZ,BRD1/2/3/4/9,BRPF3,CECR2,CREBBP,BACE1,SMARCA2/4,BRG1,BRM,CBP,etal.

TR-FRET/AlphaScreen

Immnotherapyrelated

ARG,CD,CTLA4,GITRL,IDO,MAT2A,NAMPT,PD-1,TDO,TIGIT,TPH,etal.

Colorimetric/Fluorogenic

Others

COX,Myeloperoxidase,FAAH,FABP4,HAT,Lipoxygenase,PAD,PAFAcetylhydrolase,sPLA2(TypeV),PPARγ,etal.

FP/colorimetric/Fluorogenic