抗猪

BioX cell/InVivoMAb antimouse CD209b (SIGNR1)/BE0220/5MG

The22D1monoclonalantibodyreactswithmouseCD209balsoknownasSIGN-R1.CD209bisa37kDatypeIItransmembraneC-typelectinreceptor.CD209bisexpressedonthesurfaceofsplenicmarginalzoneandlymphnodemedullarymacrophagesandiscommonlyusedasaMarkerforthesecells.TheCD209bproteinisinvolvedintheinnateimmuneresponse,itbindstoandinitiatesuptakeofvariousmicroorganismsbyrecognizinghigh-mannose-containingglycoproteinsontheirenvelopes.The22D1antibodyhasbeenreportedtoblockCD209binvivo.

Isotype

ArmenianHamsterIgG, κ

RecomendedIsotypeControl(s)InVivoMAbpolyclonalArmenianhamsterIgG
RecommendedInVivoPureDilutionBufferInVivoPurepH7.0DilutionBuffer
Immunogen

C-terminalpeptideofmouseSIGN-R1

ReportedApplications
  • invivoSIGN-R1blockade
  • Immunohistochemistry(frozen)
  • Westernblot
  • Flowcytometry
Endotoxin
  • <2EU/mg(<0.002EU/μg)
  • DeterminedbyLALgelclottingassay
Purity
  • >95%
  • DeterminedbySDS-PAGE
Formulation
  • PBS,pH7.0
  • Containsnostabilizersorpreservatives
Sterility

0.2μMfiltered

Production

Purifiedfromtissueculturesupernatantinananimalfreefacility

Purification

ProteinG

Storage

Undilutedat4°Cinthedark

References
SDSSheet

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