多聚物

2007-05-24【文摘发布】多聚物受体通过亚结构分子印迹识别叶酸及相关化合物

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Title:PolymericReceptorsfortheRecognitionofFolicAcidandRelatedCompoundsviaSubstructureImprinting

Author:AndrewJ.Hall,MilenaQuaglia,PanagiotisManesiotis,ErsiliaDeLorenzi,andBörjeSellergren

Resource:AnalyticalChemistry,2006,78(24):8362-8367.

Abstract:
Arangeof2-acrylamidopyridines,showingsubtledifferencesinsolutionbindingtowardcarboxylicacids,hasbeeninvestigatedasfunctionalmonomersinmolecularimprinting.ImprintingofN-Z-L-glutamicacidwithonesuchmonomerisshowntobeeffectiveinthecreationofamolecularlyimprintedpolymer(MIP)withrecognitionpropertiesforitstemplateandalsoforlargermoleculescontainingglutamicacidresidues.IncomparisontoaMIPpreparedviaamore"trADItional"approach,thenewpolymericreceptorsexhibitreducednonspecificbinding.Thenewreceptorsarecomparedwithpreviouslyreportedurea-basedreceptorstargetingtheglutamicacidresidueandreceptorstargetingthepteridinesubstructureoffolicacid.

PMID:17165828
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回复:时间:2007-05-24

本人已认领该文编译,48小时后若未提交译文,请其他战友自由认领

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回复:时间:2007-05-24

Title:PolymericReceptorsfortheRecognitionofFolicAcidandRelatedCompoundsviaSubstructureImprinting标题:多聚物受体通过亚结构分子印迹识别叶酸及相关化合物Author:AndrewJ.Hall,MilenaQuaglia,PanagiotisManesiotis,ErsiliaDeLorenzi,andBörjeSellergren作者:AndrewJ.Hall,MilenaQuaglia,PanagiotisManesiotis,ErsiliaDeLorenzi,andBörjeSellergrenResource:AnalyticalChemistry,2006,78(24):8362-8367.来源:分析化学,2006,78(24):8362-8367Abstract:Arangeof2-acrylamidopyridines,showingsubtledifferencesinsolutionbindingtowardcarboxylicacids,hasbeeninvestigatedasfunctionalmonomersinmolecularimprinting.摘要:因2-丙烯醛氨基吡啶类物质在溶液中与羧酸结合显示出微小差别,故将其作为分子印迹的功能单体进行研究。ImprintingofN-Z-L-glutamicacidwithonesuchmonomerisshowntobeeffectiveinthecreationofamolecularlyimprintedpolymer(MIP)withrecognitionpropertiesforitstemplateandalsoforlargermoleculescontainingglutamicacidresidues.用此类单体做N-Z-L-谷氨酸分子印迹,可以有效的制备对谷氨酸及含有谷氨酸片段的较大分子有识别特性的分子印迹聚合物(MIP)。IncomparisontoaMIPpreparedviaamore"trADItional"approach,thenewpolymericreceptorsexhibitreducednonspecificbinding.与用较“传统”的方法制备的MIP相比,新聚合物受体的非特异性结合作用减小。Thenewreceptorsarecomparedwithpreviouslyreportedurea-basedreceptorstargetingtheglutamicacidresidueandreceptorstargetingthepteridinesubstructureoffolicacid.将新受体与先前报道的以谷氨酸为靶向的尿基受体和以合成叶酸的喋啶为靶向的受体进行了比较。PMID:17165828

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回复:时间:2007-06-03

编译:(中文字符:215)多聚物受体通过亚结构分子印迹识别叶酸及相关化合物2-丙烯醛氨基吡啶类物质在溶液中与羧酸结合显示出微小差别,故AndrewJ.Hall等人将此类物质作为分子印迹的功能单体进行研究。(AnalyticalChemistry,2006,78(24):8362-8367)结果发现,用2-丙烯醛氨基吡啶类物质做N-Z-L-谷氨酸分子印迹,可以有效制备对谷氨酸及含有谷氨酸片段的较大分子有识别特性的分子印迹聚合物(MIP)。而且与用较“传统”的方法制备的MIP相比,新聚合物受体的非特异性结合作用减小。将新受体与先前报道的以谷氨酸为靶向的尿基受体及以合成叶酸的喋啶为靶向的受体进行了比较。(丁香)

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回复:时间:2007-05-26

谢谢ginnyran!而最后一句中"arecomparedwith"译成"将...与...作了比较"是否更合适?

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回复:时间:2007-06-02

ala的意见有道理。这样读着通顺很多。已改正!