微型移动性健康监测 Soft Microfluidic Assemblies of Sensors, Circuits, and Radios for the Skin
论文摘要
如果一位孕妇或一名罹患慢性疾病的患者能够将某种用于监测其健康的昂贵医院设备—如心电图(ECG)机—带回家中，那会是怎样的一副情景呢?由Sheng Xu及其同事所采用的一种非常接近这种构想的新的方法，这种方法通过可舒适地附着于一个人皮肤上的薄的、具有弹性的装置并以无线方式进行电生理数据监测;他们所用的新的方法包括了悬浮于液体中的传感器、电路及无线电微型组建。他们说，这种技术具有在诊所范围之外提供持续的、具有医院品质的医疗监测的潜力。通过软性微流控与结构性粘性表面的结合及受到控制的机械屈曲，Xu及其他的研究人员能够设计出可拉伸的电路板——它具有微型的电子元件，这些元件通过弯曲形的相互联系网络而连接在一起;该电路板悬浮在多聚物溶液中并受到硅酮橡胶膜的牵制。他们的新的策略将这类医疗检测装置的延展性及机械顺应性同时改善了几个数量级，且研究人员提出，这些软性、柔韧性的装置有一天将可从患者自己舒适的家中提供有关他们的准确、实时的健康信息。
Abstract
When mounted on the skin, modern sensors, circuits, radios, and power supply systems have the potential to provide clinical-quality health monitoring capabilities for continuous use, beyond the confines of traditional hospital or laboratory facilities. The most well-developed component technologies are, however, broadly available only in hard, planar formats. As a result, existing options in system design are unable to effectively accommodate integration with the soft, textured, curvilinear, and time-dynamic surfaces of the skin. Here, we describe experimental and theoretical approaches for using ideas in soft microfluidics, structured adhesive surfaces, and controlled mechanical buckling to achieve ultralow modulus, highly stretchable systems that incorporate assemblies of high-modulus, rigid, state-of-the-art functional elements. The outcome is a thin, conformable device technology that can softly laminate onto the surface of the skin to enable advanced, multifunctional operation for physiological monitoring in a wireless mode.

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