Namingmousestrains

Thereareinternationallyacceptedrulestonametransgenicandknock-outmice.Seethefollowinglinks:

MouseNomenclatureRulesandGuidelines

Thesearesuggestionsabouthowtonamemice,followingtheabovequotedrules:

Transgenicmice:

promoterandgenecombinedacronym^mutation-founder#-mouse#

example:lckB6-16-123example:eµSVIRTA2^tm-2-65

Breedingoftwotransgenicstrainswillbe:

promoterandgenecombinedacronyms^mutation-mouse#

example:CD19Cre-CMVHAB6^lox-8

Thepromoterandgenenamesmaybecombinedinordertohaveaveryshort,butexplicative4-6letterheADIngStrainhasbeenomitted,becausemostofthemiceusedareoutbred.Inbredlinesmaybeindicatedafterthefounderwithaniforinbred.micearenumberedsequentiallyastheyareborn.Aprogressivenumberingisusedforeachline.Thiswillallowtoeidentificationofmice,andanuniquenumberforeachmouseintheline.

Knock-outmice(Targetedmutations):

gene^mutation-EScellclone-mouse#

example:B6^D-T1/8-28

TransgenicandKObreeding:

KOnameTGacronym^mutation-mouse#

example:p53^null-lckB6-123example:B6^D-MD4-65

Individualmicewillbereportedas

Transgenics:

^TGor^TG/-or^TG/TGwhentransgenics

Knock-out:

+/+or+/-or-/-+/+,+/DandD/D

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