ACTICHROME® Heparin (antiFXa), activity assay（肝素抗Xa活性发色底物法试剂盒）相关交流-蚂蚁淘在线

ACTICHROME® Heparin (antiFXa), activity assay（肝素抗Xa活性发色底物法试剂盒）

mayitao /发布时间:1628530202 /浏览量:445

货号：	832
样本：	25μL
应用：	枸橼酸钠抗凝血浆
检测方法：	发色底物法
检测限：	0-0.8U/mL
供应商：	AmericanDiagnosticaInc
数量：	大量
规格：	100tests

ACTICHROME®Heparin(anti-FXa),activityassay
肝素抗Xa活性发色底物法试剂盒

INTENDEDUSE
ACTICHROME®Heparin(anti-FXa)isachromogenicassayintendedforthequantitativedeterminationofunfractionatedandlowmolecularweightheparinsinhumanplasmabymeasurementoffactorXainhibition.

PRINCIPLE
TheinhibitoryeffectofantithrombinIII(AT-III)onthrombin,factorXaandothercoagulationserineproteasesinplasmaisincreasedseveralthousandfoldbyheparin.Thisinhibitionaccountsfortheanticoagulanteffectofheparin.Thequantitativedeterminationofplasmaheparinlevelsbythe
measurementoftheiranti-Xaactivityisanecessarytoolformonitoringtreatmentefficacy.

Lowmolecularweightheparin(LMWH)preparationsappeartocatalyzethereactionbetweenfactorXaandAT-IIImorereadilythanthereactionbetweenthrombin(FIIa)andAT-III.Unfractionatedheparin(UFH)catalyzesbothreactionsequally.ThefactorXainhibitiontestisthemostusefulassay
coveringthewidestvarietyofheparinpreparations.Intheassay,therateoffactorXainhibitionisdirectlyproportionaltotheheparinconcentrationsincebothfactorXaandAT-IIIareinexcess.TheresidualfactorXaactivityisinverselyproportionaltotheheparinconcentration.1,2

温馨提示：不可用于临床治疗。

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