Medimabs/Amyloid precursor protein cleaved by caspase-6 Rabbit Polyclonal Antibody/MM-0142 -- anti-Amyloid precursor pro

价格
¥7100.00
货号:MM-0142--anti-Amyloidprecursorproteincleavedbycaspase
浏览量:127
品牌:Medimabs
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商品描述
  • ProductName
    Amyloidprecursorproteincleavedbycaspase-6RabbitPolyclonalAntibody
  • Host
    Rabbit
  • Clonality
    Polyclonal
  • DataSHEET
    ViewDatasheet(PDF)
  • Conjugation
    None
  • Reactivity
    Human
  • Specificity
    ISEVKMD
  • Format
    50µl
  • Background
    Amyloidprecursorprotein(APP)functionsasacellsurfacereceptorinthesynapsesofneuronsandisimplicatedinneuritegrowth,neuronaladhesion,axonogenesisandcellmobility.APPisknownastheprecursormoleculewhoseproteolysisgeneratesbetaamyloid(Aβ).DefectsinAPParethecausesofAlzheimer"sdiseasetype1andofamyloidosiscerebroarterial.CaspaseactivationhasbeenfoundtohaveacentralroleinneuronaldeathandchronicneurodegenerationssuchasHuntington"s,Parkinson"sandAlzheimer"sdiseases.ProteolyticcleavageofspecificsubstrateshasalsobeendemonstratedtobeanimportantcellulareventinthepathogenesisofADandinhibitionofcleavageofAPPbycaspase-6wasdemonstratedtosuppresssynapseloss,dentategyralatrophy,andmemoryloss.
Medimabs公司的重点仍然是同样的好处,提供新的创新服务和一个完整的“一站式商店”,为您的所有抗体需求。Founded in 2006, in Montreal, Quebec, by a group of McGill University researchers to ensure affordable access by local researchers to the latest high-quality research antibodies. Our goal was to offer custom antibody generation services and provide better, faster and cheaper than most research laboratories could do it for themselves. 品牌货号名称规格Medimabs1018Leu-enkephalin Mouse Monoclonal Antibody (NOC1)0.5mlMedimabs1019Serotonin Rat Monoclonal Antibody (YC5/45)0.5mlMedimabs1020Somatostatin Rat Monoclonal Antibody (YC7)0.5ml