• ProductName
  ProcathepsinLMouseMonoclonalAntibody(HCL)
• Host
  Mouse
• Clonality
  Monoclonal
• CloneID
  HCL
• DataSHEET
  ViewDatasheet(PDF)
• Isotype
  IgG1
• Conjugation
  None
• Reactivity
  Mouse
• Specificity
  Pro-formofcathepsin
• Format
  200µg
• Background
  ProcathepsinLisalysosomalcysteineproteinase,memberofthepeptidaseC1familyofproteins.TheprocathepsinLisaprecursorformofcathepsinL,secretedfromvariouscells.Itplaysamajorroleinintracellularproteincatabolism.Itssubstratesincludecollagenandelastin,aswellasalpha-1proteaseinhibitor,animportantcontrollingelementofneutrophilelastaseactivity.ProcathepsinLhasbeenimplicatedinseveralpathologicprocesses,includingmyofibrilnecrosisinmyopathiesandinmyocardialischemia,andintherenaltubularresponsetoproteinuria.

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