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蚂蚁淘在线 / 品牌中心 / Medimabs / Medimabs/Phospho Prion Protein (pPrP Ser43) Rabbit Polyclonal Antibody/MM-0112 -- anti-Phospho Prion Protein/50 µl

Medimabs/Phospho Prion Protein (pPrP Ser43) Rabbit Polyclonal Antibody/MM-0112 -- anti-Phospho Prion Protein/50 µl

价格
￥7100.00
货号：MM-0112--anti-PhosphoPrionProtein
浏览量：127
品牌：Medimabs
服务
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商品描述
  • ProductName
    PhosphoPrionProtein(pPrPSer43)RabbitPolyclonalAntibody
  • Host
    Rabbit
  • Clonality
    Polyclonal
  • DataSHEET
    ViewDatasheet(PDF)
  • Conjugation
    None
  • Reactivity
    Mammals
  • Format
    50µl
  • Background
    Prionrelatedneurodegenerativediseases,calledtransmissIBLespongiformencephalopathies,areobservedinmanyanimalspecies.Thesediseasesinvolveconversionofnormalcellularprionprotein(PrPc)intoaformthatisinsolubleandresistanttoproteases(PrPSc).Theproteaseresistantformcanpolymerizeintofibrilswhichaccumulateininfectedtissuesandcausecelldeathandtissuedamage.PrPshaveanN-terminalsignalsequenceandaC-terminallinkagetoglycosylphosphatidylinositolanchor.Thematureproteinisaglycosylatedproteinthatassociateswithcellmembranes.PhosphorylationofPrPCatSer-43byCdk5promotesproteinaseKresistance,prionaggregation,andfibrilformationinvitro.Inaddition,Ser-43phosphorylationisupregulatedinscrapie-infectedmousebrainrelativetocontrols.Thus,phosphorylationofSer-43maybeanimportantmechanismleADIngconversionofPrPctoPrPScandtheonsetofdisease.TheantibodywasraisedagainstPhosphoPrionProtein(pPrPSer43).
Medimabs公司的重点仍然是同样的好处，提供新的创新服务和一个完整的“一站式商店”，为您的所有抗体需求。Founded in 2006, in Montreal, Quebec, by a group of McGill University researchers to ensure affordable access by local researchers to the latest high-quality research antibodies. Our goal was to offer custom antibody generation services and provide better, faster and cheaper than most research laboratories could do it for themselves. 品牌货号名称规格Medimabs1018Leu-enkephalin Mouse Monoclonal Antibody (NOC1)0.5mlMedimabs1019Serotonin Rat Monoclonal Antibody (YC5/45)0.5mlMedimabs1020Somatostatin Rat Monoclonal Antibody (YC7)0.5ml