• ProductName
  LowdensitylipoproteinreceptorLDLRRabbitPolyclonalAntibody
• Host
  Rabbit
• Clonality
  Polyclonal
• Immunogen
  Theantibodyrecognizesthec-terminalportionofLDLR
• DataSHEET
  ViewDatasheet(PDF)
• Conjugation
  None
• Reactivity
  Rat
• Specificity
  C-terminal
• StorageBuffer
  Lyophilizedantibodycanbekeptat4ºCforupto3monthsandshouldbekeptat-20ºCforlong-termstorage
• Format
  100µl
• Background
  TheLDLReceptor(LDLR)isatransmembraneproteinof839aminoacidsthatmediatestheendocytosisofcholesterol-richLDL.TheLDLreceptorplaysacriticalroleincholesterolhomeostasis.Itbinds,internalizes,andremovesLDLfromserum.LDLRrecognizestheapoproteinB100whichisembeddedinthephospholipidouterlayerofLDLparticles,aswellastheapoEproteinfoundinchylomicronremnantsandVLDLremnants(IDL).Tobeinternalized,thereceptor-ligandcomplexesmustfirstclusterintoclathrin-coatedpits(orbuds)onthecellsurface.DefectsinLDLRarethecauseoffamilialhypercholesterolemia,acommonautosomalsemi-dominantdiseasethataffectsabout1in500individuals.

Medimabs公司的重点仍然是同样的好处，提供新的创新服务和一个完整的“一站式商店”，为您的所有抗体需求。Founded in 2006, in Montreal, Quebec, by a group of McGill University researchers to ensure affordable access by local researchers to the latest high-quality research antibodies. Our goal was to offer custom antibody generation services and provide better, faster and cheaper than most research laboratories could do it for themselves. 品牌货号名称规格Medimabs1018Leu-enkephalin Mouse Monoclonal Antibody (NOC1)0.5mlMedimabs1019Serotonin Rat Monoclonal Antibody (YC5/45)0.5mlMedimabs1020Somatostatin Rat Monoclonal Antibody (YC7)0.5ml