ProductSpecification:

AlternativeName:	CRADD,CaspaseandRIPadaptorwithdeathdomain,RIP-associatedproteinwithadeathdomain
Host:	Rabbit
Immunogen:	SyntheticpeptidecorrespondingtoaportionofhumanRAIDD.
UniProtID:	P78560
GenBankID:	U79115
Speciesreactivity:	Human,Rat Hamster,Monkey
Applications:	IHC,WB
RecommendedDilutions/Conditions:	Immunohistochemistry(1:50) WesternBlot(1:500,colorimetric) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication.
ApplicationNotes:	Detectsabandof~24kDabyWesternblot.
PurityDetail:	Peptideaffinitypurified.
Formulation:	Liquid.Inboratebufferedsaline,pH8.2,containing25mMsodiumborate,100mMboricacid,75mMsodiumchloride,and5mMEDTA(disodiumsalt).
Handling:	Avoidfreeze/thawcycles.
Shipping:	ShippedonBlueIce
LongTermStorage:	-20°C
ScientificBackground:	RAIDD(RIP-associatedICH-1/CED-3-homologousproteinwithDD)alsoknownasCRADD(caspaseandRIPadapterwithDD)containsaDD(deathdomain)andaCARD(forcaspaserecruitmentdomain)whichinteractwithRIPandcaspase,respectively,totransducedeathsignals.RAIDDisconstitutivelyexpressedinmanytissuesandmediatesapoptosiscausedbyFasandTNF-R1.

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