ProductSpecification:

AlternativeName:	ProteinkinaseCinhibitorprotein,Protein1054
Clone:	22-ii-D8B
Host:	Mouse
Isotype:	IgG
Immunogen:	Lysedtransformedhumanamnioncells(AMA).
UniProtID:	P31946(14-3-3beta),P63104(14-3-3zeta)
Gene/ProteinIdentifier:	NP_003395(RefSeqof14-3-3beta),NP_663723(RefSeqof14-3-3zeta)
Speciesreactivity:	Human,Mouse,Rat Bovine,Dog,Monkey,Porcine,Rabbit,Sheep
Applications:	ICC,IHC,WB
RecommendedDilutions/Conditions:	WesternBlot(1µg/ml,ECL) Suggesteddilutions/conditionsmaynotbeavailableforallapplications. Optimalconditionsmustbedeterminedindividuallyforeachapplication.
PurityDetail:	ProteinGaffinitypurified.
Formulation:	Liquid.InPBS,pH7.2,containing0.1mMPMSF,50%glycerol,and0.09%sodiumazide.
Shipping:	ShippedonBlueIce
LongTermStorage:	-20°C
ScientificBackground:	14-3-3proteinsarehighlyconservedproteinsthatplayaroleinbothsignaltransductionandprogressionthroughthecellcyclebybindingtoandregulatinganumberofdifferentproteins.14-3-3proteinsactivatetyrosineandtryptophanhydroxylasesandproteinkinaseC.Theymediatesignaltransductionbybindingtophosphoserine-containingproteins.Thereareatleast7mammalianisoforms.

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