2-Iminothiolanehydrochloride(Traut"sReagent)isausefulreagentforconvertingprimaryaminefunctionalgroupsintofreesulfhydrylgroups.Traut"sreagent(2-IT)isasimplewatersoluble,ringedmoleculethatcompletesthisprimaryamine(-NH2)tosulfhydryl(-SH)conversionreactioninaone-stepprocedureinthepHrangeof7to10.Oncemodificationofaproteinmoleculewith2-Iminothiolaneiscomplete,freeaminegroupswillhavebeenirreversIBLyconvertedtoasulfhydrylgroupwithafouratomchainandwithoutsignificantdisruptionoftheoriginalaminegroupsprotonationstate.

AfterincorporationoftheTraut"sfreesulfhydrylintoaproteinorotherwise,this-SHgroupmakesforaveryusefulhandleforfurthermodification,suchasselectivelyreactingthismodifiedproteinwithaSMCCorBMPScontainingconjugates,creatingapermanentbondbetweentwoproteins.A2-IminothiolanemodifiedproteinorpeptidecouldalsobeusedtocreateareversiblelinkwithanSPDPcontainingconjugate.Pleasefeelfreetocontactourtechnicalsupportstaffforfurtherquestionsspecificallyrelatedtoyourapplication.

PackageSizes:500mgand1gram

ProductNumbers:14104-500mgand14104-1g

ProductName:2-Iminothiolane

AlternativeNames:2-IT;Traut"sReagent;4781-83-3;2-IminothiolaneHCl;2-Iminothiolanehydrochloride;Dihydro-2-(3H)-thiopheniminehydrochloride;Dihydro-2-(3H)-thiophenimineHCl;C₄H₈ClNS

Specifications

Appearance:WhiteSolid

Purity:is≥90%byquantitativeNMR

Storage:4°C,protectedfrommoisture

 

PropertiesPhysicalState:Solid

CAS#:4781-83-3

ChemicalFormula:C₄H₈ClNS

MolecularWeight:137.63

Spacerlength:8.1Å

MeltingPoint:198-201°C(Lit)

TariffCode:2934.99.9000

Covachem-4-甲氧六氟丁酰氯（4-CB）描述价钱数量购买包装尺寸：5 x 1克SKU：12207-5x1$ 99.00加包装尺寸：10克SKU：12207-10$ 189.00加包装尺寸：25克SKU：12207-25$ 379.00加全部添加到购物车描述发送4-carbethoxyhexafluorobutyrl chloride（4-CB）是一种烷基化试剂，用于衍生化样品以改善气相色谱分离。在进行GC分析之前，可以使用4-CB衍生化血液样本中的苯丙胺代谢物。包装尺寸：5 x 1克和25克产品编号：12207-5x1和12207-25产品名称：4-甲氧六氟丁酰氯（4-CB）备用名称：4-Carbethoxyhexafluorobutyrl chloride; 4-CB; 乙基六氟戊二酰氯技术指标外观：无色透明液体纯度：≥98％储存：4°C，防潮特性物理状态：液体CAS＃：18381-53-8化学式：C 7 H 5 ClF 6 O 3分子量：286.56沸点：159°C（升）比重：1.47（升）