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蚂蚁淘在线 / 品牌中心 / Abnova / Abnova/A2M purified MaxPab mouse polyclonal antibody (B01P)/1kit/H00000002-B01P
商品描述
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human A2M protein.
- Immunogen:
- A2M (AAH40071.1, 1 a.a. ~ 1474 a.a) full-length human protein.
- Sequence:
- MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYINGITYTPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGRGHARLVHVEEPHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEVKSKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKDLGNA
- Host:
- Mouse
- Reactivity:
- Human
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Storage Buffer:
- In 1x PBS, pH 7.4
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- MSDS:
Download
- Interspecies Antigen Sequence:
- Mouse (72); Rat (73)
- Datasheet:
- Download
- Applications
- Western Blot (Tissue lysate)
- A2M MaxPab polyclonal antibody. Western Blot analysis of A2M expression in human liver.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of A2M expression in transfected 293T cell line (H00000002-T01) by A2M MaxPab polyclonal antibody.Lane 1: A2M transfected lysate(162.14 KDa).Lane 2: Non-transfected lysate.
- Protocol Download
- Application Image
- Western Blot (Tissue lysate)
- enlarge
- Western Blot (Transfected lysate)
- enlarge
- Gene Information
- Entrez GeneID:
- 2
- GeneBank Accession#:
- BC040071.1
- Protein Accession#:
- AAH40071.1
- Gene Name:
- A2M
- Gene Alias:
- CPAMD5,DKFZp779B086,FWP007,S863-7
- Gene Description:
- alpha-2-macroglobulin
- Omim ID:
- 103950, 104300
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
- Other Designations:
- -
- Interactome
- Gene Pathway
- Complement and coagulation cascades
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis
- Arthritis, Rheumatoid
- Cardiovascular Diseases
- Cognition Disorders
- Dementia
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Progression
- Diseases in Twins
- Edema
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease
- Hepatitis C, Chronic
- Kidney Failure, Chronic
- Liver Cirrhosis
- Macular Degeneration
