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Abnova/NGFR monoclonal antibody, clone NGFR5/1kit/MAB3735

价格
面议
货号:MAB3735
浏览量:127
品牌:Abnova
服务
全国联保
正品保证
正规发票
签订合同
商品描述
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native NGFR.
  • Immunogen:
  • Native purified NGFR from A875 melanoma cells.
  • Host:
  • Mouse
  • Reactivity:
  • Baboons, Cat, Domestic ferret, Human, Monkey, Rabbit
  • Specificity:
  • Recognizes p75 NGFR. Does NOT react with rat or mouse.
  • Form:
  • Liquid
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Datasheet:
  • PDF DownloadDownload
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4804
  • Gene Name:
  • NGFR
  • Gene Alias:
  • CD271,Gp80-LNGFR,TNFRSF16,p75(NTR),p75NTR
  • Gene Description:
  • nerve growth factor receptor (TNFR superfamily, member 16)
  • Omim ID:
  • 162010
  • Gene Ontology:
  • Hyperlink
  • Gene Summary:
  • Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq
  • Other Designations:
  • low affinity nerve growth factor receptor,low-affinity nerve growth factor receptor,nerve growth factor receptor
  • Gene Pathway
  • Cytokine-cytokine receptor interaction
  • Neurotrophin signaling pathway
  • Related Disease
  • Alzheimer Disease
  • Alzheimer disease
  • Asperger Syndrome
  • Asthma
  • Asthma
  • Attention Deficit Disorder with Hyperactivity
  • Autistic Disorder
  • Bronchiolitis, Viral
  • Celiac Disease
  • Depressive Disorder
  • Depressive Disorder, Major
  • Disease Models, Animal
  • Eating Disorders
  • Genetic Diseases, Inborn
  • Genetic Predisposition to Disease
  • Infant, Premature, Diseases
  • Kidney Failure, Chronic
  • Mental Disorders
  • Multiple Sclerosis
    • ... see more
Abnova的Abnova Diagnostics F蛋白表达系统基于小麦胚芽的真核翻译设备。小麦胚在浓缩干燥状态下储存所有翻译成分,一旦发芽就准备好进行蛋白质合成。常规的小麦胚芽提取物包含RNA N-糖苷酶三丁酸酯和其他翻译抑制剂,例如硫蛋白,核糖核酸酶,脱氧核糖核酸酶和蛋白酶。这些抑制剂来自胚乳。大量洗涤小麦胚芽以消除胚乳污染物已导致提取物具有高度的稳定性和活性。通过将具有5'cap和多(RSA)尾巴的mRNA与该提取物与专有脂质体结合使用,进行体外翻译反应产生足够量的膜蛋白,该膜蛋白被脂质体捕获,导致正确的构象和生物学功能必不可少的折叠。该系统相对于普遍使用的蛋白质表达平台(例如大肠杆菌,昆虫细胞和哺乳动物细胞)具有明显优势,这些平台都是体内系统,并且在细胞膜的约束下导致产量和稳定性低。此外,体外小麦胚芽系统适于自动化以用于高通量小分子以及生物学筛选和表征。