- Product Description:
- IL4 (Human) ELISpot Kit is a sandwich enzyme-based immunospot assay for the quantitative measurement of human IL4.
- Storage Instruction:
- Store the kit at 4°C.
- Protocol:
Protocol Download
- Detection Method:
- Colorimetric
- Regulation Status:
- For research use only (RUO)
- Datasheet:
- Download
- Gene Alias:
- BCGF-1,BCGF1,BSF1,IL-4,MGC79402
- Gene Description:
- interleukin 4
- Gene Summary:
- The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
- Other Designations:
- B cell growth factor 1,B_cell stimulatory factor 1,lymphocyte stimulatory factor 1
- Allograft rejection
- Asthma
- Autoimmune thyroid disease
- Cytokine-cytokine receptor interaction
- Fc epsilon RI signaling pathway
- Hematopoietic cell lineage
- Jak-STAT signaling pathway
- T cell receptor signaling pathway
- Abortion, Habitual
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Adenocarcinoma
- Aggressive Periodontitis
- AIDS Dementia Complex
- Albuminuria
- Alcoholism
- Alveolar Bone Loss
- Alveolitis, Extrinsic Allergic
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Juvenile Rheumatoid
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Autoimmune Diseases
- Bacteremia
- Biliary Tract Neoplasms
- Bone Diseases
- Brain Ischemia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Bronchial Hyperreactivity
- Bronchiolitis
- Bronchiolitis, Viral
- Bronchopulmonary Dysplasia
- Brucellosis
- Cadaver
- Calcinosis
- Candidiasis
- Candidiasis, Vulvovaginal
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cardiomyopathy, Dilated
- Cardiovascular Diseases
- Celiac Disease
- Central Nervous System Neoplasms
- Cerebral Infarction
- Cerebrovascular Accident
- Chagas Disease
- Chlamydia Infections
- Cholecystolithiasis
- Choledocholithiasis
- Chorioamnionitis
- Chronic Disease
- Chronic Periodontitis
- Cognition Disorders
- Colitis, Ulcerative
- Colon cancer
- Colonic Neoplasms
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Common Variable Immunodeficiency
- Communicable Diseases
- Conjunctivitis
- Connective Tissue Diseases
- Constriction, Pathologic
- Coronary Artery Disease
- Coronary Disease
- Crohn Disease
- Crohn"s disease
- Cystitis, Interstitial
- Dengue
- Dental Plaque
- Dermatitis, Allergic Contact
- Dermatitis, Atopic
- Dermatitis, Occupational
- Dermatomyositis
- Diabetes Complications
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Progression
- Disease Susceptibility
- Drug Hypersensitivity
- Ductus Arteriosus, Patent
- Edema
- Endometriosis
- Enterocolitis, Necrotizing
- Epidermal Necrolysis, Toxic
- Epilepsy
- Esophageal Neoplasms
- Esophagitis
- Fatigue Syndrome, Chronic
- Fetal Diseases
- Fetal Membranes, Premature Rupture
- Fibromyalgia
- Food Hypersensitivity
- Gastritis
- Gastritis, Atrophic
- Genetic Predisposition to Disease
- Gingival Hemorrhage
- Glioblastoma
- Glioma
- Glomerulonephritis, IGA
- Gout
- Graft vs Host Disease
- Graves Disease
- Graves Ophthalmopathy
- Hashimoto Disease
- Helicobacter Infections
- Hematologic Diseases
- Hemophilia A
- Hemophilia A
- Hepatitis B
- Hepatitis B, Chronic
- Hepatitis C
- Hepatitis C, Chronic
- Hepatitis, Toxic
- Herpesviridae Infections
- Histiocytosis, Langerhans-Cell
- HIV Infections
- Hodgkin Disease
- Hyperglycemia
- Hyperparathyroidism, Secondary
- Hypersensitivity
- Hypersensitivity, Immediate
- Hypertension
- Idiopathic Pulmonary Fibrosis
- Infant, Premature, Diseases
- Infection
- Inflammation
- Inflammatory Bowel Diseases
- Intervertebral Disk Displacement
- Inversion, Chromosome
- Irritable Bowel Syndrome
- Kidney Diseases
- Kidney Failure
- Kidney Failure, Chronic
- Kidney Neoplasms
- Leiomyoma
- Leishmaniasis, Cutaneous
- Leptospirosis
- Leukemia
- Leukemia, chronic myeloid
- Leukemia, Myeloid, Chronic
- Lichen Planus, Oral
- Liver Cirrhosis
- Liver Cirrhosis, Alcoholic
- Liver Diseases
- Liver Neoplasms
- Lung Diseases
- Lung Diseases, Interstitial
- Lung Neoplasms
- Lupus Erythematosus, Systemic
- Lymphatic Metastasis
- Lymphoma
- Lymphoma, AIDS-Related
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Malaria
- Malaria, Cerebral
- Malaria, Falciparum
- Malignant melanoma
- Melanoma
- Meningococcal Infections
- Mental Disorders
- Metabolic Syndrome X
- Metaplasia
- Migraine Disorders
- Mitral Valve Prolapse
- Mouth Neoplasms
- Mucocutaneous Lymph Node Syndrome
- Multiple Myeloma
- Multiple Organ Failure
- Multiple Sclerosis
- Multiple Trauma
- Musculoskeletal Diseases
- Myocardial Infarction
- Myocardial Ischemia
- Myositis
- Nasal Polyps
- Neoplasm Invasiveness
- Neoplasms
- Nephrosis, Lipoid
- Nephrotic Syndrome
- Neuropsychological Tests
- Obesity
- Obesity
- Obstetric Labor, Premature
- Occupational Diseases
- Osteoarthritis
- Osteolysis
- Osteomyelitis
- Osteoporosis
- Otitis Media
- Pain
- Pancreatic cancer
- Pancreatic Neoplasms
- Paracoccidioidomycosis
- Parasitemia
- Parasitic Diseases
- Parkinson Disease
- Parkinson disease
- Pemphigoid, Bullous
- Pemphigus
- Peptic Ulcer
- Periodontal Attachment Loss
- Periodontal Pocket
- Periodontitis
- Periodontitis, Juvenile
- Placenta Diseases
- Polymyositis
- Postoperative Complications
- Precancerous Conditions
- Pre-Eclampsia
- Pregnancy Complications
- Pregnancy Complications, Hematologic
- Pregnancy Complications, Infectious
- Premature Birth
- Prenatal Exposure Delayed Effects
- Prostate cancer
- Prostatic Hyperplasia
- Prostatic Neoplasms
- Prosthesis Failure
- Psoriasis
- Psychiatric Status Rating Scales
- Pulmonary Disease, Chronic Obstructive
- Pulmonary Fibrosis
- Purpura, Thrombocytopenic, Idiopathic
- Q Fever
- Radiation Injuries
- Radiation Pneumonitis
- Recurrence
- Respiratory Hypersensitivity
- Respiratory Sounds
- Respiratory Syncytial Virus Infections
- Retinal Vein Occlusion
- Rheumatic Heart Disease
- Rhinitis
- Rhinitis, Allergic, Perennial
- Rhinitis, Allergic, Seasonal
- Sarcoidosis
- Sarcoidosis, Pulmonary
- Sarcoma, Kaposi
- Schistosomiasis japonica
- Schistosomiasis mansoni
- Schizophrenia
- Schizophrenia
- Sciatica
- Scleroderma, Systemic
- Seizures, Febrile
- Sepsis
- Severe Acute Respiratory Syndrome
- Shock
- Sjogren"s Syndrome
- Skin Diseases
- Skin Neoplasms
- Skin Ulcer
- Spondylitis, Ankylosing
- Staphylococcal Infections
- Stevens-Johnson Syndrome
- Stomach Neoplasms
- Stroke
- Subacute Sclerosing Panencephalitis
- Sudden Infant Death
- Temporal Arteritis
- Thoracic Neoplasms
- Trachoma
- Trypanosomiasis, African
- Tuberculosis
- Tuberculosis, Pulmonary
- Urinary Bladder Neoplasms
- Urticaria
- Uterine Neoplasms
- Vaginosis, Bacterial
- Viremia
- Vitiligo
- Waldenstrom Macroglobulinemia
- Werner syndrome
Abnova的Abnova Diagnostics F蛋白表达系统基于小麦胚芽的真核翻译设备。小麦胚在浓缩干燥状态下储存所有翻译成分，一旦发芽就准备好进行蛋白质合成。常规的小麦胚芽提取物包含RNA N-糖苷酶三丁酸酯和其他翻译抑制剂，例如硫蛋白，核糖核酸酶，脱氧核糖核酸酶和蛋白酶。这些抑制剂来自胚乳。大量洗涤小麦胚芽以消除胚乳污染物已导致提取物具有高度的稳定性和活性。通过将具有5'cap和多（RSA）尾巴的mRNA与该提取物与专有脂质体结合使用，进行体外翻译反应产生足够量的膜蛋白，该膜蛋白被脂质体捕获，导致正确的构象和生物学功能必不可少的折叠。该系统相对于普遍使用的蛋白质表达平台（例如大肠杆菌，昆虫细胞和哺乳动物细胞）具有明显优势，这些平台都是体内系统，并且在细胞膜的约束下导致产量和稳定性低。此外，体外小麦胚芽系统适于自动化以用于高通量小分子以及生物学筛选和表征。
