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商品描述
MEK 1/2 Antibody
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Product Description | This antibody was developed and affinity purified using a peptide based on human MEK1. This antibody was tested to be able to detect both human MEK1 and MEK2 using human cell lysates. |  Representative western blot with anti-MEK1/2 (1:1000) using, from left to right, 10 µg, 20 µg and 40 µg of 293 cell lysate. | |
Species | Rabbit | ||
Formulation | 1000 µg/mL in TBS with 50% glycerol | ||
Immunogen | MEK1 peptide (210-255 aa) KLH conjugates Protein code: Q02750 | ||
Purification | Affinity specific affinity chromatography | ||
Specificity | Recognizes both MEK1 and MEK 2 , human and mouse | ||
Applications | ELISA (>1:2000); WB (>1:1000); IP (5 µg/mg protein) | ||
Scientific Description | MEK1 is a member of the dual specificity protein kinase family that acts as a mitogen-activated protein kinase (MAPK) kinase. MEK1 lies upstream of MAPK/ERK and stimulates the enzymatic activity of MAPK/ERK upon a wide variety of extra- and intracellular signals. As an essential component of MAPK/ERK signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. | ||
Storage & Stability | Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly. |
