ProductDescription
DaunorubicinisananthracyclinedrugusedthatkillingcellsbyinhibitingDNAandRNAsynthesis.ItintercalatesbetweenbasepairsandinteractswithtopoisomeraseII,thereforeinhibitingDNAreplicationandrepairandRNAsynthesis.DaunorubicinwasinitiallyisolatedfromStreptomycespeucetius.
Invitro,daunorubicininhibitstheproliferationofvarioustumorcellsatmicromolarlevel.(1)Clinically,ithasbeenusedintreatingcertaintypesofacuteleukemiaandneuroblastoma.
Technicalinformation:
| ChemicalFormula: | C27H29NO10.HCl | |
| CAS#: | 23541-50-6 | |
| MolecularWeight: | 563.98 | |
| Purity: | >98% | |
| Appearance: | orangered | |
| ChemicalName: | (8S,10S)-8-acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione,monohydrochloride | |
| Solubility: | Upto100mMinDMSO | |
| Synonyms: | Daunorubicinhydrochloride |
ShippingCondition:Theproductisshippedinaglassvialatambienttemperature.
Storagecondition:Forlongershelflife,storesolidpowderat4oCdesiccated,orstoreDMSOsolutionat-20oC.
Reference:
| 1. | GewirtzDA,Acriticalevaluationofthemechanismsofactionproposedfortheantitumoreffectsoftheanthracyclineantibioticsadriamycinanddaunorubicin.BiochemPharmacol.1999;57(7):727-41.PubmedID:10075079 |
Cellagen的ChamQ SYBR qPCR预混液(无ROX)| Q321产品描述ChamQSYBR®qPCR预混液(Vazyme,#Q321)由香槟Taq DNA聚合酶(Vazyme,#P122)通过抗体修饰的热启动激活技术保护,是专为基于SYBR Green I的定量PCR(qPCR)设计的。ChamQSYBR®qPCR Master Mix的优化缓冲液系统中的独特因素(即促进特异性的Exactor)大大提高了其灵敏度和特异性。该混合物以2倍反应浓度制备,可直接用于鲁棒性低模板qPCR,具有高灵敏度,特异性和可靠性。优点特异性+敏感性的最佳组合。独特的抗体修饰的热启动taq,具有独特的特异性促进因子。Mg2 +和染料的最佳浓度。


