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indoor biotechnologies/Recombinant Asp f 1.0101 (RP-AF1-1)/1/RP-AF1-1

价格
¥11500.00
货号:RP-AF1-1
浏览量:127
品牌:indoor biotechnologies
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商品描述
Allergen:rAsp f 1 (Aspergillus fumigatus allergen 1.0101), Common mold
Unit:250µg
Source: Pichia pastoris
Mol. Wt:18kD
Purification:Purified by multi-step HPLC. Purity on silver-stained SDS-PAGE >95%.
Concentration:

See product insert.

Formulation:

Preservative-free and carrier-free in phosphatebuffered saline, pH 7.4. Filtered through 0.22µm filter.

Storage:Store at -20ºC.Avoid repeated Freeze/Thaw cycles.
Notes:

1) rAsp f 1 has a C-terminal 6x His-tag.

2)Upper band is Asp f 1 dimer.

Product Resources:

Recombinant Asp f 1Certificate of Analysis

Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:
  1. Arruda, LK, Platts-Mills, TAE, Fox, JW and Chapman, MD (1990). Aspergillus fumigatus allergen I, a major IgE binding protein, is a member of the mitogillin family of cytotoxins. J. Exp. Med., 172:1529-1532.
  2. Arruda LK, Platts-Mills TAE, Longbottom JL, Chapman MD (1992). Aspergillus fumigatus: Identification of 16kd, 18kd and 45kd antigens recognized by human IgG and IgE antibodies and murine monoclonal antibodies. J. Allergy Clin. Immunol. 89:1166-1176.
  3. Arruda LK, Mann BJ, Chapman MD (1992). Selective expression of a major allergen and cytotoxin, Asp f I, in Aspergillus fumigatus. J. Immunol.149:3354-3359.
  4. Sporik RB, Arruda LK, Woodfolk J, Chapman MD, Platts-Mills TAE. (1993). Environmental exposure to Aspergillus fumigatus allergen 1 (Asp f I). Clin Exp Allergy 23:326-331.
  5. El-Dahr JM, Fink R, Selden R, Arruda LK, Platts-Mills TAE, Heymann PW. (1994). Development of immune responses to Aspergillus at an early age in children with cystic fibrosis. Am J Respir Crit Care Med 150:1513-1518.

indoor biotechnologies很高兴将其重组蛋白的开发工作扩展到包括与过敏和哮喘有关的病毒蛋白。人鼻病毒16(HRV-16)表面蛋白VP1,VP2和VP0(VP2和VP4的融合体)被高质量生产。HRV衣壳蛋白提供了有用的工具,可用于研究鼻病毒诱发的哮喘加重所涉及的免疫机制,以及用于表位作图,T细胞反应和诊断目的。由于广泛的蛋白质-蛋白质相互作用,鼻病毒蛋白质难以单独表达。通过使用专有的纯化和制造方案,Indoor Biotechnologies开发了许多HRV-16 VP1,VP2和VP0,这些均已通过Western blotting验证。