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indoor biotechnologies/Natural Bos d 5 (NA-BD5-1)/1/NA-BD5-1

价格
¥11500.00
货号:NA-BD5-1
浏览量:127
品牌:indoor biotechnologies
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商品描述
Allergen:nBos d 5 (β-Lactoglobulin), Cow"s milk
Unit:250µg
Source: Partially purified Bovine milk
Mol. Wt:18 kD
Purification:

Column chromatography. Purity on silver stained SDS-PAGE >95%.

Concentration:

See product insert. Based on OD 280 nm.Extinction coefficient = 0.94

Formulation:

Preservative and carrier-free in endotoxin free phosphatebuffered saline, pH 7.4. Filtered through 0.22µm filter.

Storage:Store at -20ºC
Notes:β -Lactoglobulin runs at 18 kD with dimer at 36 kD on non-reducing SDS-PAGE.
PDB:
Product Resources:

Natural Bos d 5 Certificate of Analysis

Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:
  1. Alexander LJ, Hayes G, Pearse MJ, Beattie CW, Stewart AF, et al. Complete sequence of the bovine beta-lactoglobulin cDNA. Nucleic Acids Res 1989;17(16):6739.
  2. Roth-Walter F, Pacios LF, Gomez-Casado C, Hofstetter G, Roth GA, et al. The major cow milk allergen Bos d 5 manipulates T-helper cells depending on its load with siderophore-bound iron. PLoS One. 2014; 9(8): e104803.
  3. Luyt D, Ball H, Makwana N, Green MR, Bravin K, et al. BSACI Guideline for the Diagnosis and Management of Cow"s Milk Allergy. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology. 2014.
  4. Fiocchi A, Bouygue GR, Albarini M, Restani P. Molecular diagnosis of cow’s milk allergy. Curr Opin Allergy Clin Immunol. 2011 Jun;11(3):216-21.
  5. Kuwata K, Hoshino M, Forge V, Era S, Batt CA, Goto Y. Solution structure and dynamics of bovine beta-lactoglobulin A. Protein Sci. 1999 Nov;8(11):2541-5.
indoor biotechnologies很高兴将其重组蛋白的开发工作扩展到包括与过敏和哮喘有关的病毒蛋白。人鼻病毒16(HRV-16)表面蛋白VP1,VP2和VP0(VP2和VP4的融合体)被高质量生产。HRV衣壳蛋白提供了有用的工具,可用于研究鼻病毒诱发的哮喘加重所涉及的免疫机制,以及用于表位作图,T细胞反应和诊断目的。由于广泛的蛋白质-蛋白质相互作用,鼻病毒蛋白质难以单独表达。通过使用专有的纯化和制造方案,Indoor Biotechnologies开发了许多HRV-16 VP1,VP2和VP0,这些均已通过Western blotting验证。