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indoor biotechnologies/LoTox™ Recombinant Phl p 5a (LTR-PP5A-1) [Replaces 1mg Lyophilized LTR-PP5A-4]/1/LTR-PP5A-1

价格
¥13700.00
货号:LTR-PP5A-1
浏览量:127
品牌:indoor biotechnologies
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商品描述
Allergen:rPhl p 5a (Phleum pratense allergen 5a), Timothy
Unit:250ug
Source: E. coli
Mol. Wt:~28 kD

Purification:

Multi-step chromatographic purification. Purity > 95 % by SDS-PAGE

Concentration:

See product insert.

Formulation:

Insterile, endotoxin free 1x PBS, pH 7.4

Storage:Store at -20ºC; Avoid repeated Freeze/Thaw cycles.
Notes:

(1) A LoTox™ product: Endotoxin <0.03 EU/µg.

(2) LoToxTM rPhl p 5a has a C-terminal 7xHis-tag

Genbank:AJ555152
PDB:1L3P
Product Resources:LoTox™ Recombinant Phl p 5a Certificate of Analysis
Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:
  1. Niederberger V, Laffer S, Froschl R, Kraft D, et al. IgE antibodies to recombinant pollen allergens (Phl p 1, Phl p 2, Phl p 5, and Bet v 2) account for a high percentage of grass pollen-specific IgE. J Allergy Clin Immunol 1998;101:258-64.
  2. Mari A. Skin test with a timothy grass (Phleum pratense) pollen extract vs. IgE to a timothy extract vs. IgE to rPhl p 1, rPhl p 2, nPhl p 4, rPhl p 5, rPhl p 6, rPhl p 7, rPhl p 11, and rPhl p 12: epidemiological and diagnostic data. Clin Exp Allergy 2003;33:43-51.
  3. Jutel M, Jaeger L, Suck R, et al. Allergen-specific immunotherapy with recombinant grass pollen allergens. J Allergy Clin Immunol 2005;116:608-13.
indoor biotechnologies很高兴将其重组蛋白的开发工作扩展到包括与过敏和哮喘有关的病毒蛋白。人鼻病毒16(HRV-16)表面蛋白VP1,VP2和VP0(VP2和VP4的融合体)被高质量生产。HRV衣壳蛋白提供了有用的工具,可用于研究鼻病毒诱发的哮喘加重所涉及的免疫机制,以及用于表位作图,T细胞反应和诊断目的。由于广泛的蛋白质-蛋白质相互作用,鼻病毒蛋白质难以单独表达。通过使用专有的纯化和制造方案,Indoor Biotechnologies开发了许多HRV-16 VP1,VP2和VP0,这些均已通过Western blotting验证。