Description:Horseradish peroxidase (HRP) conjugated mouse monoclonal antibody to human luteinizing hormone (LH)

Purification:Protein G affinity purified

Product Type:HRP conjugated detection antibody in matched antibody pair.

Target Protein:HumanLHβ subunit

Immunogen:HumanLHβsubunit

Fusion Myeloma:Not known

Specificity:HumanLHβsubunit

Species Reacitvity: Human, others not tested

Host / Isotype: Mouse, IgG1 Kappa

Storage Buffer Formulation:Mixture of 50% glycerol and 50% PH7.2 0.01M PBS. Final PH = 7.0 ± 0.1.

Storage: Store at -20^oC

Research Area:Hormone,ovulation

Background:

In the female menstrual cycle, during a 24-48 hour period, luteinizing hormone (LH) is rapidly released from gonadotropic cells in pituitary gland as a result of positive feedback regulation by the elevated estrogen during follicle maturation. The LH surge triggers the release of mature egg from ovarian follicle and the development of remaining follicle into corpus luteum. Progesterone secreted by corpus luteum is needed for preparing the endometrium for egg implantation. LH is critical for ovulation in women. In men, LH stimulates testis to produce testosterone.

LH has an αsubunit that is identical to the one in other glycoprotein hormones such as TSH, FSH and HCG. LH level is used for predicating ovulation in women to increase the chance of insemination.

Application:

ELISA:In combination with capture antibody, anti-LH a mAb LH-1 (MO-M40048B), the antibody can be used for LH detection in sandwich ELISA application.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.