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yesbiotech/pAb Rabbit anti-NF-κB-p65 (RelA)/0.1 mg/AI70006A

价格
¥4500.00
货号:AI70006A
浏览量:127
品牌:yesbiotech
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商品描述
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Description

Details

Description:Rabbit anti-NF-κB p65 polyclonal antibody

Purification: Protein G affinity purified

Product Type:Primary antibody

Target Protein:NF-κB p65

Immunogen:A synthetic peptide (IIEQPKQRGMRFR) derived from the p65 protein of NF-κB complex, conjugated with KLH for immunization.

Specificity:This antibody is reactive to the synthetic NF-κB p65 peptide (IIEQPKQRGMRFR)

Species Reacitvity:Mouse, human and other species with consensus NF-κB p65 peptide (IIEQPKQRGMRFR)

Source:Rabbit

Formulation:Lyophilized in pH 7.4, 0.01M PBS

Reconstitution:Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Storage:Store at -20oC

Research Area:Life science research, stem cell factor signalling, cancer research

Background:

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a transcription factor that controls the transcription of many genes that are associated with immuno-response, anti-apoptosis, neuroplasticity and memory. There are five NF-κB proteins in mammals: RelA(NF-κB p65), RelB, c-Rel, NF-κB (NF-κB p105), and NF-kB2 (NF-κB p100). They form a variety of homodimers and heterodimers, each of which activates its own distinctive set of genes. P65 has been shown to be involved with DNA binding.

Application:

Western blot:The antibody (1:6,000 diluted) can detect the 65kDa NF-κB-p65 in Hela cells on Western blot.

Other applications have not been evaluated.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.

Additional

Additional Information

Product SpecificitypAb Rabbit anti-NF-κB-p65 (RelA)
ApplicationWB
Size0.1 mg
yesbiotech自2009年以来,我们一直在开发针对AD的基于抗体的疗法,并针对多种淀粉样β(Aβ)肽产生了70多种单克隆抗体(mAb)。这些单克隆抗体中的三个(3F5、6C8和1H3)已显示出在小鼠模型中预防AD进展的功效。我们还开发了一种ELISA试剂盒,用于定量测量AD的主要病因Aβ42。我们的AD前项目是首次尝试通过鼻内途径将抗Aβ42单抗用于AD预防和治疗。