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Symansis/Cripto-1/25 µg/3081

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¥5220.00
货号:3081
浏览量:127
品牌:Symansis
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Cripto-1

Catalog Number: 3081Availability: In StockSize:5 µg, 10 µg, 25 µgUniprot Nu :P13385Species Reactivity :HumanHost :Human, HEK Cell Expessed
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Cripto-1DescriptionMSDS

Cripto-1 is the founding member of the EGF-CFC gene family, which is conserved among vertebrates. Proteins within this family contain a signal sequence, a characteristic EGF-like domain, a cysteine-rich region termed the cryptic (CFC) motif, and a hydrophobic C- terminus. It has been reported that Cripto-1 is O-fucosylated on Thr-88 and that this modification is required for the physical interaction with Nodal as well as for signalling activity. We have confirmed that Cripto-1B is O-fucosylated at this site

Tags:3081C,3081D,3081H,P13385
Symansis的抑制剂阵列Easy50™阵列是连续稀释的药物阵列,已知它们专门靶向某些细胞信号分子。这些可直接应用于基于酶或细胞的测定,以达到跨越EC 50  和IC 50 的最终浓度 适合该药物的分子靶标。使用生成的信息,研究人员可以快速确定特定的细胞信号通路是否参与正在研究的生物过程。阵列的形式是一个96孔微孔板,包含12列,每列有一种或多种抑制剂,以及8行,每列包含该抑制剂的渐进稀释液,最后一行除外,该行留空作为阴性对照。对于每种抑制剂范围的稀释液从该抑制剂的IC的大约十分之一50 到一成百倍的IC 50