CD-209L-Fc Chimera
Symansis" DCSIGNR - Fc Chimera/CD209L - Fc Chimerahcx is a glycoprotein containing 5-25% carbohydrate by weight. A drop in the observed MW after treatment with PNGase F indicates that Symansis" DCSIGNR - Fc Chimera/CD209L - Fc Chimerahcx is N-glycosylated. Symansis" CD209L-Fchcx may also be O-glycosylated Densitometry of protein isoforms visualised by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein. 1D SDS-PAGE of Symansis" hcx protein before and after treatment with glycosidases to remove oligosaccharides. A drop in the observed MW after treatment indicates the presence of glycosylation. 1. Koppel EA, et al. (2005) Cell Microbiol. 7: 157-65. | |  |
