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Symansis/BAFF/5 µg/8001

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¥6300.00
货号:8001
浏览量:127
品牌:Symansis
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商品描述

BAFF

Catalog Number: 8001Availability: In StockSize:2 μg, 5 µgUniprot Nu :Q9Y275 Species Reactivity :HumanHost :Human, HEK Cell Expessed
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BAFFDescriptionMSDS

BAFF is a type II membrane protein that functions predominantly as a B cell survival factor and specifically promotes the proliferation and survival of activated B cells by inducing expression of pro-survival oncogenes. BAFF is expressed by T cells, dendritic cells, macrophages and neutrophils.Densitometry of protein isoforms visualised by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein.BAFF binds to three different receptors: the transmembrane activator and calcium modulator cyclophilin ligand intercator (TACI), B cell maturation antigen (BCMA) and BAFF receptor (BAFFR). These are expressed on B cells and the BAFFR is also expressed on T cells suggesting BAFF may play a role in T cell activation.

Tags:TNFSF13B;BAFF,BLYS,TALL1,TNFSF20,ZTNF4,8001B,8001C,Q9Y275
Symansis的抑制剂阵列Easy50™阵列是连续稀释的药物阵列,已知它们专门靶向某些细胞信号分子。这些可直接应用于基于酶或细胞的测定,以达到跨越EC 50  和IC 50 的最终浓度 适合该药物的分子靶标。使用生成的信息,研究人员可以快速确定特定的细胞信号通路是否参与正在研究的生物过程。阵列的形式是一个96孔微孔板,包含12列,每列有一种或多种抑制剂,以及8行,每列包含该抑制剂的渐进稀释液,最后一行除外,该行留空作为阴性对照。对于每种抑制剂范围的稀释液从该抑制剂的IC的大约十分之一50 到一成百倍的IC 50