
品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com

商品描述

BEZ235, BEZ-235, NVP-BEZ235
Catalog Number: SY-BEZ235Availability: In StockSize: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg CAS Number :915019-65-7Alternative Names:BEZ235, NVP-BEZ235
Qty:
BEZ235, BEZ-235, NVP-BEZ235DescriptionMSDS
BEZ235 is a potent dual inhibitor of PI3K and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anticancer agents when used in in vivo combination studies. It inhibits PI3K isoforms and mutants with low nanomolar IC50 values, leading to growth arrest in the G1 phase. Through its effects on PI3K, BEZ235 inhibits VEGF-induced angiogenesis. By directly blocking cell growth and indirectly inhibiting angiogenesis, it has potential in both solid tumors and in metastatic melanoma therapy. | ![]() |