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Symansis/CRP/C-Reactive Protein Rapid Human ELISA Kit/96 Well Kit/ECRPSY

价格
¥11200.00
货号:ECRPSY
浏览量:127
品牌:Symansis
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CRP/C-Reactive Protein Rapid Human ELISA Kit

Catalog Number: ECRPSYAvailability: In StockUniprot Nu :P02741Species Reactivity :HumanApplications :ELISAAlternative Names:PTX1
*Well Kit:
Qty:
CRP/C-Reactive Protein Rapid Human ELISA KitDescriptionMSDS

C-reactive protein (CRP) is a circulating protein mainly secreted from the liver. This acute phase protein consists of five identical non-glycosylated subunits of 23 kDa, that give rise to a symmetrically arranged globular protein with molecular weight of approximately 120 kDa.(1) It has long been recognized that CRP is closely related to immunology, inflammation and host defense, as a result it has been used as an inflammatory marker. However, the development of high-sensitivity CRP (hsCRP) ELISA had addressed its role in other clinical issues. There is accumulating evidence suggesting the important role that CRP plays in mediating cardiovascular diseases (CVD) and type 2 diabetes.(2-4) Normally CRP is presenting only in a trace amount in circulation (<1 ug/ml)(5-6) but can increase over 1,000-fold under acute inflammatory state. Individual with blood CRP levels <1 ug/ml, 1-3 ug/ml and >3 ug/ml is considered to have low, moderate and high risk, respectively, of CVD and myocardial infraction.(7) Therefore, blood CRP level has become a promising measure of CVD risk.(8-9)1. Thompson D., Pepys M.B. and Wood S.P. (1999) Structure, 7, 169-177.2. Festa A, D’Agostino R. Jr., Tracy R.P. and Haffner S.M. (2002) Diabetes, 51, 1131-1137.3. Verma S. and Yeh E.T. (2003) Am J Physiol, 285, R1253-R1258.4. Jialal I., Devaraj S. and Venugopal S.K. (2004) Hypertension, 44, 6-11.5. Kindmark C.O. (1972) Scand J Clin Lab Invest, 29, 407-411.6. Macy E.M., Hayes T.E. and Tracy R.P. (1997) Clin Chem, 43, 52-58.7. Ridker P.M. (2004) Am Heart Hosp J, 2(4 Suppl 1), 4-9.8. Benzaquen l.R., Yu H. and Rifai N. (2002) Crit Rev Clin Lab Sci, 39, 459-497.9. Pearson T.A. et al., (2003) Circulation, 107, 499-511.

Tags:ECRPSY,PTX1,P02741
Symansis的抑制剂阵列Easy50™阵列是连续稀释的药物阵列,已知它们专门靶向某些细胞信号分子。这些可直接应用于基于酶或细胞的测定,以达到跨越EC 50  和IC 50 的最终浓度 适合该药物的分子靶标。使用生成的信息,研究人员可以快速确定特定的细胞信号通路是否参与正在研究的生物过程。阵列的形式是一个96孔微孔板,包含12列,每列有一种或多种抑制剂,以及8行,每列包含该抑制剂的渐进稀释液,最后一行除外,该行留空作为阴性对照。对于每种抑制剂范围的稀释液从该抑制剂的IC的大约十分之一50 到一成百倍的IC 50