| Source | M.W. | 4963.55 | CAS No. | ||
|---|---|---|---|---|---|
| Structural Info | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH | ||||
| Formulation | Lyophilized in a solution of acetonitrile and TFA. | ||||
| Reconstitution | Before reconstitution, werecommend a brief spin to drive down any material dislodged from the bottom ofthe tube. The lyophilized peptide shouldbe reconstituted in sterile PBS. | ||||
| Stability | The lyophilized protein isstable for at least 1 year if stored at -80 °C. Reconstituted protein is stable for at least 1 month at 4 °C, but shouldbe stored in aliquots at -80 °C for longer term. Avoid repeated freeze andthaw. | ||||
| Purity | Greater than 95% as determined by RP-HPLC analysis | ||||
| Biological Activity | |||||
| Country of Origin | USA | ||||
Thymosinsare small polypeptides originally isolated from the thymus, but most areactually present in many other tissues. The archetypical β-Thymosin isThymosin-β4, which is a cellular constituent in many tissues. In addition toits role as a major actin-sequestering molecule, Thymosin-β4 has a role intissue repair. Such effect have been shown in animal models of tissue damageand now in human clinical trials. Recently,Thymosin-β4 was shown to stimulate regeneration of adult cardiac progenitorcells in a paper published in Nature (Smart,et al., Nature, 2011, June 8th). AminoAcid Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH
