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Stemrd/Follistatin like-3 Fc fusion, human recombinant/50 µg/FL3FC-050

价格
¥7900.00
货号:FL3FC-050
浏览量:127
品牌:Stemrd
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全国联保
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签订合同
商品描述
SourceHuman 293 CellsM.W.CAS No.
Structural Info
FormulationLyophilized in sterile filtered solution of PBS.
ReconstitutionBefore reconstitution, abrief spin is recommend to drive down any material dislodged from the bottom ofthe tube. The lyophilized protein shouldbe reconstituted in sterile H2O to a desired concentration.
StabilityThe lyophilized protein isstable for at least one year if stored at -80 °C. Reconstituted protein is stable for at least fourweeks at 4 °C, but should be stored in aliquots at -80 °C forlonger term. Avoidrepeated freeze and thaw.
PurityGreater than 95% as determined by SDS-PAGE analysis
Biological ActivityThe activity was determined by using a SMAD reporter gene assay in cultured human cells.The IC50 ranges from 100 - 500 ng/ml in the inhibition of 1 ng/mL Activin A activity.
Country of OriginUSA

Follistatin like 3 is a homolog of Follistatinwhich is a secreted protein that binds to some members of the TGF-β family and blockstheir access to corresponding receptors. In addition to being a natural antagonist ofActivins, Follistatin like 3 mayinhibit the activity of other TGF-β ligands including BMPs, Myostatin, GDF-11,and TGF-β1. StemRD’s Follistatin like 3 Fc fusion protein is full-length human Follistain like 3 fused to theN-terminus of the Fc domain of human IgG1. This fusion allowsstabilization of the protein in vitro and in vivo and dimerization of therecombinant protein rendering high-affinity binding to Activins. Expression is in human 293 cells cultured inserum-free and protein-free medium. Purification of the fusion protein from culture medium is achieved byusing protein A chromatography.

Product Sheet
Stemrd的Y-27632,(1R,4r)-4-((R)-1-氨乙基)-N-(吡啶-4-基)环己烷-羧酰胺-2HCl,是一种Rho相关激酶(ROCK)抑制剂。Y27632已被证明可以防止凋亡,并提高解离的人类胚胎干(ES)细胞的存活率和克隆效率,而不会影响其多能性。