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商品描述
| Source | M.W. | CAS No. | |||
|---|---|---|---|---|---|
| Structural Info | |||||
| Formulation | Lyophilized in a solution of acetonitrile and TFA. | ||||
| Reconstitution | Before reconstitution, we recommend abrief spin to drive down any material dislodged from the bottom of thetube. The lyophilized peptide shouldbe reconstituted in 10mM HCl or acetic acid. | ||||
| Stability | The lyophilized protein is stable forat least 1 year if stored at -80 °C. Reconstituted protein is stable for at least 1 month at 4 °C, butshould be stored in aliquots at -80 °C for longer term. Avoidrepeated freeze and thaw. | ||||
| Purity | Greater than 95% as determined by RP-HPLC analysis | ||||
| Biological Activity | Not determined. | ||||
| Country of Origin | USA | ||||
The Notch pathway is an important pathway in stem cellfunctions. Jagged-1 is a ligand forNotch receptors. This peptide with asequence of CDDYYYGFGCNKFCRPR has been shown to mimic thefunction of full-length Jagged-1, and therefore, can be used as an agonist toactivate the Notch pathway.Ref:Nickoloff et al, Cell DeathDifferent, 2002; Sato T et al, Nature,2009
Product Sheet
Nickoloff et al, Cell Death Different, 2002; Sato T et al, Nature, 2009
