Mag-Fura-2isaUV-excitablefluorescentindicatorformagnesiumwithaKdof1.9mM(1,2).SimilartoFura-2,theexcitationwavelengthofMag-Fura-2undergoesablueshiftfrom369nmto330nm.Mag-Fura-2alsorespondstoCa2butwithasignificantlylowerKdthanFura-2forCa2.AnimportantapplicationofMag-Fura-2isitsuseindetectinghigh,transientCa2concentrationduringCa2spikes(3,4).Mag-Fura-2/tetraammoniumsaltcanbeloadedintocellsbymicroinjectionorscrapeloADIng.AlsoseeMag-Fura-2,tetrasodiumsalt(50036)andthecellmembrane-permeantMag-Fura-2AMester(50037,50038,50039).
- Lightyellowsolidsolubleinwater(pH>6)
- Storeat-20°Candprotectfromlight
- C18H10K4N2O11
- MW:587
- [132319-57-4]
References
1.PNAS86,2981(1989).
2.AmJPhysiol256,C540(1989).
3.Neuron10,21(1993).
4.BiophysJ68,2156(1995).