BAPTAanditsderivativesarecalciumchelatorsthatarecommonlyusedtoformcalciumbufferswithwell-definedcalciumconcentrations.ByinjectingthechelatorsintocellsorbyincubatingcellswiththeAMesterformofthechelators,onecancontrolthecytosoliccalciumconcentration,animportantmeanstostudytherolesofcalcium.
KeyadvantagesofthesecalciumchelatorsincluderelativeinsensitivitytowardintracellularpHchangeandfastreleaseofcalcium.BiotiumoffersseveralBAPTAchelatorswithcalciumdissociationconstantscoveringtheBIOLOGicallysignificantrangefrom10-7to10-2M.
- Kd(noMg2):0.59uM,Kd(1mMMg2):0.70uM
- Whitesolidsolubleinwater
- Storeat4°C
- C23H24Na4N2O10
- MW:564.36
- [73630-11-2]
References
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