In vivo DogtorMag™ Transfection Reagent has been designed for in vivo targeted transfection of various types of nucleic acids such as DNA, RNA, oligonucleotides using magnetic nanoparticles coated with synthetic lipids (In vivo DogtorMag). DNA complexes can be easily administrated through various injection routes such as systemic administration (intravenous, intra-artery) or local administration (intratumoral, intracerebroventricular).
In vivo Magnetofection™ main advantages in comparison to other procedures:
Increased transfection efficiency
Targeted process (magnetically-driven)
Reduction of the systemic dissemination of vectors during injection
Reduction of the vector doses
Work under non permissive conditions (hypothermia, physiological flow conditions)
Penetration of the vector into tissues
Minimized toxicity
Universal – suitable for all nucleic acids
In vivo DogtorMag kit contains In vivo Dogtor transfection reagent + In vivo CombiMag transfection reagent
Storage: In vivo Dogtor -20°C / In vivo CombiMag + 4°C
Shipping conditions: Room temperature
- NB: This reagent needs to be used with a magnet.
