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商品描述
BIOLOGICAL INFORMATION
DescriptionThis C-terminally labeled biotin ACTH (1-39) has been used in ELISA assays. Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a cleavage product from a larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal cortex by acting through a cell membrane receptor (ACTH-R). In mammals, the action of ACTH is limited to those areas of the adrenal cortex in which the glucocorticoid hormones cortisol (hydrocortisone) and corticosterone are formed. ACTH has little control over the secretion of aldosterone, the other major steroid hormone from the adrenal cortex.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10959
CAS No.N/A
NameBiotinyl-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-ValGly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-GluAsp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH
Chemical NameBiotinyl-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-ValGly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-GluAsp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH
Purity≥98%
SynonymsBiotin-ACTH (1-39), human
FormulaC217H322N58O60S
Molecular Weight4767.47
One Letter CodeBiotin-SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
Three Letter CodeBiotinyl-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-ValGly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-GluAsp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH
SMILESN/A
InChI KeyN/A
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.Moreno-Guzmán, M. et al. Biosensors Bioelectronics 35, 82 (2012)
2.Elias, LL. and AJ. Clark, Braz J Med Biol Res 33, 1245 (2000)
3.Latronico, AC. Braz J Med Biol Res 33, 1249 (2000)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
