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商品描述
BIOLOGICAL INFORMATION
DescriptionWKYMVm is a synthetic peptide isolated from mixtures of random hexapeptide sequences. The peptide stimulates phosphoinositide hydrolysis in several hematopoietic cell lines (U937, HL-60, U266) and human neutrophils. It also induces superoxide generation in human neutrophils (Seo et al, 1997). WKYMVm also attenuates death by apoptosis of monocytes, induced by serum starvation
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10845
CAS No.187986-11-4
NameW Peptide, WKYMVm
Chemical NameW-Peptide,-WKYMVm
Purity≥98%
SynonymsN/A
Formula C41H61N9O7S2
Molecular Weight857.1
One Letter CodeWKYMVm
Three Letter CodeTrp-Lys-Tyr-Met-Val-d-Met
SMILESCC(C)C(C(=O)NC(CCSC)C(=O)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CCCCN)NC(=O)C(CC2=CNC3=CC=CC=C32)N
InChI KeyFMBGOORJEKQQLG-LXOXETEGSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Baek et al (1996) Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries. J.Biol.Chem. 271 8170 PMID: 8626507
2.Christophe et al (2001) The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/Lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J.Biol.Chem. 276 21585 PMID: 11285256
3.Christophe et al (2002) Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1 /LXA4R, is not affected by lipoxin. Scand.J.Immunol. 56 470 PMID: 12410796
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
