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商品描述
BIOLOGICAL INFORMATION
DescriptionThe native peptide PLARTLSVAGLPGKK is a selective substrate for CaM kinase II and PKC. It is also a poor substrate for phosphorylase kinase and is not phosphorylated by myosin light chain kinase. The sequence of PLARTLSVAGLPGKK is homologous to phosphorylation site 2 in glycogen synthase. The relative Vmax/Km ratios of the peptide for different kinases are 100 for CaMK II, 22 for PKC, 2 for phosphorylase kinase, and 0.5 for myosin light chain kinase, respectively.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10776
CAS No.108334-68-5
NameSyntide 2
Chemical NameSyntide-2
Purity≥98%
SynonymsN/A
FormulaC68H122N20O18
Molecular Weight1507.82
One Letter CodePLARTLSVAGLPGKK
Three Letter CodePRO-LEU-ALA-ARG-THR-LEU-SER-VAL-ALA-GLY-LEU-PRO-GLY-LYS-LYS
SMILESCC(C)CC(C(=O)NC(C)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)NC(=O)C2CCCN2
InChI KeyNKBRRWBNPNUBDD-TYKVATLISA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.K Barcomb., etc. Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B. Mol Pharmacol. 2013 Sep;84(6):834-43.
2.Lanteri ML, Pagnussat GC, Lamattina L. Calcium and calcium-dependent protein kinases are involved in nitric oxide- and auxin-induced adventitious root formation in cucumber. J Exp Bot. 2006;57(6):1341-51. PMID: 16531462.
3.Szczegielniak J, Klimecka M, Liwosz A, et al. A wound-responsive and phospholipid-regulated maize calcium-dependent protein kinase. Plant Physiol. 2005 Dec;139(4):1970-83. PMID: 16299185.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
