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商品描述
BIOLOGICAL INFORMATION
DescriptionKemptide is a phosphate acceptor peptide that serves as a synthetic substrate for cAMP-dependent protein kinase (PKA) (Km=16 µM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA. The sequence defines the phosphorylation site of porcine liver pyruvate kinase.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10775
CAS No.65189-71-1
NameKemptide
Chemical NameKemptide
Purity≥98%
SynonymsN/A
FormulaC32H61N13O9
Molecular Weight771.9
One Letter CodeLRRASLG
Three Letter CodeLEU-ARG-ARG-ALA-SER-LEU-GLY
SMILESCC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)NCC(=O)O)N
InChI KeyWIGDGIGALMYEBW-LLINQDLYSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Wang Z The peptide microarray-based assay for kinase functionality and inhibition study. Methods Mol Biol 570:329-37 (2009). Read more (PubMed: 19649604)
2.Portela Pet al. Evaluation of in vivo activation of protein kinase A under non-dissociable conditions through the overexpression of wild-type and mutant regulatory subunits in Saccharomyces cerevisiae. Microbiology 147:1149-59 (2001). Read more (PubMed: 11320118)
3.MacAla LJet al. TECHNICAL NOTE: measurement of cAMP-dependent protein kinase activity using a fluorescent-labeled kemptide. Kidney Int 54:1746-50 (1998). Read more (PubMed: 9844154)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
