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商品描述
BIOLOGICAL INFORMATION
DescriptionAs a well-known FPR antagonist, formyl peptide receptor antagonist Boc-Phe-Leu-Phe-Leu-Phe is used extensively in FPR research. In regard to neutrophils, it was found that treatment of mice with Boc-PLPLP results in 40% reduction in neutrophil counts recovered in bronchoalveolar lavage fluid, compared with infected mice receiving placebo.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10602
CAS No.73572-58-4
NameN-Boc-Phe-Leu-Phe-Leu-Phe
Chemical NameN-Boc-Phe-Leu-Phe-Leu-Phe
Purity≥98%
SynonymsFormylpeptide receptor antagonist
FormulaC44H59N5O8
Molecular Weight785.51
One Letter CodeN/A
Three Letter CodeBOC-PHE-LEU-PHE-LEU-PHE
SMILESCC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CC(C)C)NC(=O)C(CC3=CC=CC=C3)NC(=O)OC(C)(C)C
InChI KeyNGNZQSPFQJCBJQ-LTLCPEALSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.T.Gobbetti et al., Br. J. Pharmacol., 172, 910 (2015)
2.D.Hackel et al., J. Neuroimmunol., 230, 65 (2011)
3.P.Prieto et al., Cell Death Differ., 17, 1179 (2010)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
