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商品描述
BIOLOGICAL INFORMATION
DescriptionMagainin I is thought to preferentially bind to anionic phospholipids abundant in bacterial membranes. With the formation of dynamic peptide-lipid supramolecular pore and cell permeabilization, magainins become positively charged and amphiphatic. Binding to artificial neutral membranes has also been demonstrated.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10038
CAS No.108433-99-4
NameMagainin 1
Chemical NameMagainin-1
Purity≥98%
SynonymsN/A
FormulaC112H177N29O28S1
Molecular Weight2409.85
One Letter CodeGIGKFLHSAGKFGKAFVGEIMKS
Three Letter CodeGLY-ILE-GLY-LYS-PHE-LEU-HIS-SER-ALA-GLY-LYS-PHE-GLY-LYS-ALA-PHE-VAL-GLY-GLU-ILE-MET-LYS-SER
SMILESCCC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CC2=CNC=N2)C(=O)NC(CO)C(=O)NC(C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC3=CC=CC=C3)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CC4=CC=CC=C4)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(C(C)CC)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)O)NC(=O)CN
InChI KeyOFIZOVDANLLTQD-ZVNXOKPXSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.Novik, V. et al. (2009). Characterization of a Campylobacter jejuni VirK protein homolog as a novel vVirulence determinant. Infect Immun 77, 5428. doi: 10.1128/IAI.00528-09.
2.Morvan, A. et al. Mol. Mar. Biol. Biotechnol. 3, 327 (1994)
3.Matanic, A. et al. Int. J. Antimicrob Agents 23, 382 (2004)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
