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ESIBIO/ExoSense™ CD63 Exosome ELISA Kit/EM2203/EM2203

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¥2000.00
货号:EM2203
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品牌:ESIBIO
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ExoSense™ CD63 Exosome ELISA Kit

ExoSense™ CD63 Exosome ELISA Kit

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The ExoSense CD63 Exosome ELISA Kit is designed as a direct enzyme-linked immunosorbent assay (ELISA) for the detection of whole exosomes that are immobilized onto the surface of wells of a microtiter plate.
SKU: EM2203
$100.00

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T: 877.636.4978 E: orders@esibio.com

F: 510.648.3255

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Description

Details

The ExoSense CD63 Exosome ELISA Kit is designed as a direct enzyme-linked immunosorbent assay (ELISA) for the detection of whole exosomes that are immobilized onto the surface of wells of a microtiter plate. Detection is achieved using ExoSense CD63 Primary Antibody that specifically binds to exosomes, followed by HRP-conjugated ExoSense Secondary Antibody (goat-anti-mouse) to enhance the signal. The assay provides an accurate measurement of exosome particles per mL based on a standard curve of fibroblast derived exosomes of known concentration. Developed by ReCyte Therapeutics Inc, a subsidiary of BioTime, Inc.

Details

Details

SizeEM2203
SpeciesHuman
Sample TypesPlasma, serum, and cell culture supernatants
Assay TimeOvernight recommended
Applications
ReferencesTetta, C., et al. (2013) Extracellular vesicles as an emerging mechanism of cell-tocell communication. Endocrine 44(1): 11-19.Maguire, G. (2013) Stem cell therapy without the cells. Commun Integr Biol. 6(6): e26631.De Jong, O.G., et al. (2014) Extracellular vesicles: potential roles in regenerative medicine. Front Immunol 5: 608.Webber, J., et al. (2013) How pure are your vesicles? J Extracell Vesicles 2: 19861.

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ESIBIO的TGF-βI型受体ALK5激酶,I型激活素/淋巴结受体ALK4和I型淋巴结受体ALK7的选择性抑制剂(IC 50值分别为12、45 和7.5 nM)。A83-01阻断Smad2的磷酸化并抑制TGF-β诱导的上皮-间充质转化。仅弱抑制ALK-1,-2,-3,-6和MAPK活性。A83-01已显示抑制大鼠iPSC分化并增加克隆扩增效率。它有助于维持人iPSC的均质性和长期体外自我更新。